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emi4389-sup-0001-si.doc399K

Fig. S1. Correlation analysis of RNA-seq and qRT-PCR.

A. correlation coefficient of fold changes between RNA-seq and qRT-PCR.

B. correlation coefficient of fold changes between two batches of qRT-PCR.

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Table S1. Overview of the genome of R15 and the expression profiles of the genes.

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Table S2. Operon map of Methanolobus psychrophilus R15.

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Table S3. Verification of the transcriptomic data of 16 genes using qRT-PCR.

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Table S4. Differential transcript abundance of the genes for methanogenesis and biosynthesis from the cultures growing at 4°C versus 18°C.

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Table S5. Differential transcript abundance of genes for protein translation and processing from the cultures growing at 4°C versus 18°C.

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Table S6. Differential transcript abundance of genes for transcription and RNA processing from the cultures growing at 4°C versus 18°C.

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Table S7. Distribution of the oxygen detoxification genes in the available methanogen genomes.

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Table S8. Differential transcript abundance of the genes for antioxidation from the cultures growing at 4°C versus 18°C.

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Table S9. Signal transduction systems distributed in the genomes of the archaea growing at various temperatures.

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Table S10. Signal transduction systems in the genome of strain R15 and their temperature-responsive expression.

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