Factors influencing weight gain in an Asian population of psychiatric inpatients: A retrospective study in Taiwan

Authors

  • Yu-Tsung Liu MD,

    1. Department of Psychiatry, Chang Gung Memorial Hospital, Linkou, Taiwan
    2. School of Medicine, Chang Gung University, Taoyuan, Taiwan
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  • Yeuk-Lun Chau MS,

    1. Department of Psychiatry, Chang Gung Memorial Hospital, Linkou, Taiwan
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  • Shih-Chieh Hsu MD,

    1. Department of Psychiatry, Chang Gung Memorial Hospital, Linkou, Taiwan
    2. School of Medicine, Chang Gung University, Taoyuan, Taiwan
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  • Chun-Lin Chu MD,

    1. Department of Psychiatry, Chang Gung Memorial Hospital, Linkou, Taiwan
    2. School of Medicine, Chang Gung University, Taoyuan, Taiwan
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  • Ching-Yen Chen MD

    Corresponding author
    1. Department of Psychiatry, Chang Gung Memorial Hospital, Linkou, Taiwan
    2. School of Medicine, Chang Gung University, Taoyuan, Taiwan
    • Correspondence

      Ching-Yen Chen MD, Section of General Psychiatry, Department of Psychiatry, Chang Gung Memorial Hospital, Linkou, 5, Fu-Shin Street, Kweishan 333, Taoyuan, Taiwan.

      Tel: +886 3 3281200 ext. 2439

      Fax: +886 3 3280267

      Email: psycychen@yahoo.com.tw

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Abstract

Introduction

The aim of this study was to investigate the factors associated with weight gain by psychiatric inpatients in short-term treatment.

Methods

A total of 378 medical records were reviewed, and sociodemographic, clinical, and baseline biochemical data from 221 psychiatric inpatients were analyzed.

Results

Evaluation of baseline characteristics indicated that the following were significant predictors of weight gain: Axis I diagnosis, treatment with second-generation antipsychotics and mood stabilizers, length of stay, admission body weight, low-density lipoprotein value, triglyceride level, and triglyceride/high-density lipoprotein ratio. Multiple linear regression analysis showed that the independent predictors of weight gain were length of stay and taking both a second-generation antipsychotic and a mood stabilizer. The triglyceride/high-density lipoprotein ratio was an influencing factor inversely associated with weight gain (P = 0.063).

Discussion

Length of hospitalization and polypharmacy strongly predicted weight gain among psychiatric inpatients receiving short-term treatment.

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