Motivated by the centenary of the IRM, this article is a reflection from an indigenous perspective. Indigenous Peoples’ experience with mission movements is vast, complex and varied, depending on the context. The mission of God has always been in relation to the original peoples of the land, who have been part of the church even when these relations have been neither fair nor harmonious. Indigenous Peoples have been persecuted, demonized and excluded, as well as assimilated and westernized in order to survive, but now they are not only arising again as peoples but raising up the importance of indigenous spiritual perspectives and theological reflection. Dialogue with indigenous wisdom and theologies was mandated by the 2006 assembly of the WCC, but that necessitates recognizing and welcoming “otherness” and revisiting syncretism.