Alveolar bone and the bisphosphonates

Authors


Alastair N Goss
Professor and Director
Oral and Maxillofacial Surgery Unit
The University of Adelaide
Adelaide SA 5005
Email: oral.surgery@adelaide.edu.au
Website: http://www.dentistry.adelaide.edu.au/o&mfs/0&mfs_index.html

Abstract

Bisphosphonate associated osteonecrosis of the jaws (ONJ) usually commences at the alveolus. Comparison is made between the structure and function of long bones and alveolar bone and the differing susceptibilities of the bisphosphonates at these different sites are explored. Current concepts of the causation of ONJ are discussed. The clinical implications of these findings to dentists managing periodontal conditions are presented.

Ancillary