A case of tongue carcinoma associated with chronic graft-versus-host disease after allogeneic haematopoietic stem cell transplantation

Authors

  • K Noguchi,

    1. Department of Oral and Maxillofacial Surgery, Division of Reparative and Regenerative Medicine, Institute of Medical Science, Mie University Graduate School of Medicine, Japan.
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  • M Nakase,

    1. Department of Oral and Maxillofacial Surgery, Division of Reparative and Regenerative Medicine, Institute of Medical Science, Mie University Graduate School of Medicine, Japan.
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  • M Inui,

    1. Department of Oral and Maxillofacial Surgery, Division of Reparative and Regenerative Medicine, Institute of Medical Science, Mie University Graduate School of Medicine, Japan.
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  • S Nakamura,

    1. Department of Oral and Maxillofacial Surgery, Division of Reparative and Regenerative Medicine, Institute of Medical Science, Mie University Graduate School of Medicine, Japan.
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  • K Okumura,

    1. Department of Oral and Maxillofacial Surgery, Division of Reparative and Regenerative Medicine, Institute of Medical Science, Mie University Graduate School of Medicine, Japan.
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  • T Tagawa

    1. Department of Oral and Maxillofacial Surgery, Division of Reparative and Regenerative Medicine, Institute of Medical Science, Mie University Graduate School of Medicine, Japan.
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Dr M Inui
Department of Oral and Maxillofacial Surgery
Graduate School of Medicine
Mie University
1577 Kurimamachiya-cho
Tsu City 514-8507
Mie Prefecture
Japan
Email:m-inui@clin.medic.mie-u.ac.jp

Abstract

Graft-versus-host disease (GVHD) can occur at various sites, including the oral mucosa, where it is associated with a high risk of head and neck cancer. We report the case of a 46-year-old woman with tongue cancer that developed following Hodgkin’s lymphoma and chronic GVHD, and we discuss the possible causes of cancer development.

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