Comparison of efficacy of three commercially available dentifrices on dentinal hypersensitivity: a randomized clinical trial



This article is corrected by:

  1. Errata: Errata Volume 58, Issue 2, 272, Article first published online: 28 May 2013

  • [Correction added on 16 October 2012, after first online publication: Author list and affiliations have been corrected.]

Dr AR Pradeep
Professor and Head
Department of Periodontics
Government Dental College and Research Institute
Fort, Bangalore-560002


Background:  Dentinal hypersensitivity has been defined as a short, sharp pain arising from exposed dentine as a result of various stimuli such as heat, cold, chemical, or osmotic, that cannot be ascribed to any other pathology. This study was conducted to assess the efficacy of three commercially available toothpastes in the reduction of dentinal hypersensitivity.

Methods:  A total of 149 subjects (72 males and 77 females; aged 20 to 60 years) were entered into the study and randomly divided into four groups: Group 1 – toothpaste containing 5% potassium nitrate; Group 2 – toothpaste containing 5% calcium sodium phosphosilicate with fused silica; Group 3 – toothpaste containing 3.85% amine fluoride; and Group 4 – a placebo toothpaste. After sensitivity scores for controlled air stimulus and cold water at baseline were recorded, subjects were given toothpastes and sensitivity scores were measured again at 2 weeks and 6 weeks.

Results:  All groups showed a reduction in sensitivity scores at 2 weeks and 6 weeks. The calcium sodium phosphosilicate group was found to be significantly better compared to the other groups at the end of 6 weeks.

Conclusions:  The calcium sodium phosphosilicate group showed a better reduction in the symptoms of dentinal hypersensitivity.