What Do We Know About Risk Factors for Infection in Humans with Toxoplasma gondii and How Can We Prevent Infections?
Article first published online: 10 SEP 2009
© 2009 Blackwell Verlag GmbH
Zoonoses and Public Health
Volume 57, Issue 1, pages 8–17, February 2010
How to Cite
Petersen, E., Vesco, G., Villari, S. and Buffolano, W. (2010), What Do We Know About Risk Factors for Infection in Humans with Toxoplasma gondii and How Can We Prevent Infections?. Zoonoses and Public Health, 57: 8–17. doi: 10.1111/j.1863-2378.2009.01278.x
- Issue published online: 4 JAN 2010
- Article first published online: 10 SEP 2009
- Received for publication August 8, 2008
- Toxoplasma gondii;
- case–control study;
- food hygiene;
- risk factors
Fourteen case–control studies evaluating the importance of different risk factors for infection of humans with Toxoplasma gondii were identified. Surprisingly, up to two-thirds of infections could not be explained by risk factors such as consuming raw or undercooked meat or poor kitchen hygiene. Few studies reported population attributable risk, and when reported, it was low. Protocols including questionnaires used for collecting data, age and socio-economic groups studied, and sample sizes varied among studies. There is a need for carefully planned, case–control studies to identify sources of infection with T. gondii in humans. New risk factors, such as the manufacture of organic meat, and possible ways to sterilize meat to inactivate T. gondii tissue cysts are discussed.