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Keywords:

  • Eye diseases;
  • leptospirosis;
  • mechanisms of disease;
  • pathogenesis;
  • uveitis;
  • zoonoses

Summary

Leptospirosis, caused by pathogenic species of genus Leptospira, is a highly prevalent zoonotic disease throughout many parts of the world, and an important emerging disease within the United States. Uveitis is a common complication of systemic infection in humans. A similar condition in horses is characterized by recurrent bouts of inflammation. In this article, we review advances in our understanding of leptospiral uveitis and its pathogenic mechanisms.