Hepatitis C virus infection among HIV-1 infected individuals from northern Mexico

  1. Ana M. Rivas-Estilla1,*,
  2. Eda Ramírez-Valles1,
  3. Ramón Martinez-Hernández1,
  4. Claudia Charles-Niño1,
  5. Ericka Ramírez-Camacho2,
  6. Felix Rositas-Noriega2,
  7. Maria L. Garza-Rodriguez1,
  8. Hugo A. Barrera-Saldaña1,
  9. Karina Trujillo-Murillo1,
  10. Javier Ramos-Jimenez2

Article first published online: 17 APR 2007

DOI: 10.1111/j.1872-034X.2007.00035.x

Issue

Hepatology Research

Hepatology Research

Volume 37, Issue 5, pages 311–316, May 2007

Additional Information

How to Cite

Rivas-Estilla, A. M., Ramírez-Valles, E., Martinez-Hernández, R., Charles-Niño, C., Ramírez-Camacho, E., Rositas-Noriega, F., Garza-Rodriguez, M. L., Barrera-Saldaña, H. A., Trujillo-Murillo, K. and Ramos-Jimenez, J. (2007), Hepatitis C virus infection among HIV-1 infected individuals from northern Mexico. Hepatology Research, 37: 311–316. doi: 10.1111/j.1872-034X.2007.00035.x

Author Information

  1. 1

    Laboratory of Molecular Infectology, Department of Biochemistry, School of Medicine and

  2. 2

    Infectious Diseases Service, Department of Internal Medicine, Hospital Universitario ‘Dr Jose E. Gonzalez’, UANL, Monterrey NL, México

*Dr Ana María Rivas-Estilla, Depto. de Bioquímica, Fac. de Medicina, UANL, Av. Madero y Eduardo Aguirre Pequeño s/n, Col. Mitras Centro CP 64460, Monterrey NL, México. Email: arivas@fm.uanl.mx

Publication History

  1. Issue published online: 17 APR 2007
  2. Article first published online: 17 APR 2007
  3. Received 31 January 2006; revision 26 May 2006; accepted 27 November 2006.

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Keywords:

  • HCV genotypes;
  • HCV;
  • HIV-1;
  • HIV-1/HCV coinfection

Aims:  The prevalence of hepatitis C virus (HCV) infection, risk factors and HCV genotypes in 140 HIV-1 infected individuals from northern Mexico was determined.

Methods:  Hepatitis C infection was confirmed by the detection of anti-HCV antibodies and HCV-RNA in sera, and genotyping was performed by the InnoLiPA-HCV genotype assay.

Results:  Seventeen (12.1%) out of 140 HIV-infected individuals were found to be HCV-positive. Coinfected individuals were more likely to be male (87%). The most frequent genotype was 1a (41%), followed by 1b (29.4%), 2a/c (17.6%), 2b (5.9%) and 3 (5.9%). Serum transaminase concentrations (AST and ALT) were higher in coinfected patients. Among the risk factors for coinfection: sexual transmission was the most frequently observed (men who have sex with men (MSM); 64.7% and bisexual behavior; 64.7%) followed by intravenous drug users (IVDU) (53%). There was no association of the HCV genotypes with the age and risk factors for HIV-1 and HCV infection observed in the studied patients.

Conclusion:  The results suggest that the prevalence of HIV-1/HCV coinfection in Mexico is lower than in other American countries.

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