Effect of long-term late-evening snack on health-related quality of life in cirrhotic patients
Article first published online: 14 APR 2010
© 2010 The Japan Society of Hepatology
Volume 40, Issue 5, pages 470–476, May 2010
How to Cite
Yamanaka-Okumura, H., Nakamura, T., Miyake, H., Takeuchi, H., Katayama, T., Morine, Y., Imura, S., Shimada, M. and Takeda, E. (2010), Effect of long-term late-evening snack on health-related quality of life in cirrhotic patients. Hepatology Research, 40: 470–476. doi: 10.1111/j.1872-034X.2010.00637.x
- Issue published online: 30 APR 2010
- Article first published online: 14 APR 2010
- Received 31 July 2009; revision 3 November 2009; accepted 28 November 2009.
- dietary therapy;
- health-related quality of life;
- late-evening snack;
- liver cirrhosis;
Aim: In patients with liver cirrhosis, abnormal energy metabolism induces low health-related quality of life (HRQOL) scores. However, late-evening snack (LES) prevents morning starvation in cirrhotic patients. Our aim is to assess the effect of long-term LES on HRQOL in cirrhotic patients, using the 36-item Short Form (SF-36) health survey.
Methods: Thirty-nine cirrhotic patients classified as Child–Pugh grade A were recruited. The patients were randomly divided into two groups: 24 were assigned to the non-LES group and 15 to the LES group. SF-36 scores, anthropometric data and serum biochemical parameters were examined in the non-LES and LES groups at 0, 6 and 12 months.
Results: Neither anthropometric data nor laboratory data showed significant differences between the non-LES and the LES groups at 0, 6 and 12 months. The role–emotional (RE) HRQOL scores at 6 months and mental health (MH) scores at 6 and 12 months were significantly reduced from the baseline level in the non-LES group. In contrast, these scores remained unchanged in the LES group. General health perception (GH) scores at 12 months, RE at 6 months and MH at 6 and 12 months in the LES group were significantly higher than those of the non-LES group.
Conclusion: Long-term LES administration may be helpful in maintaining higher HRQOL in patients with cirrhosis.