This article studies 4 × 4 vehicle replacement within the International Committee of the Red Cross (ICRC), one of the largest humanitarian organizations. ICRC policy sets the replacement of vehicles at 5 years or 150,000 km, whichever comes first. Using field data collected at the ICRC headquarters and national level we study the ICRC policy. Our results suggest that the organization can make considerable savings by adjusting its replacement policy. This study contributes to the area of logistics and transportation research in humanitarian operations.