Retention in the National Institute on Drug Abuse Clinical Trials Network Women and Trauma Study: Implications for Posttrial Implementation


  • Rogério M. Pinto wrote this article with the support of a Mentored Research Development Award from the National Institute of Mental Health (Grant K01MH081787-02). The research reported in this article was supported by Grant U10DA13035 from the National Institute on Drug Abuse (PI: Nunes). The authors wish to acknowledge the work and support of the six Regional Research Training Centers involved in the implementation of the Women and Trauma Study and the invaluable commitment of the patients and staff at the seven participating community-based treatment programs.

concerning this article should be addressed to Rogério M. Pinto, Columbia University School of Social Work, 1255 Amsterdam Avenue, New York, NY 10027. Electronic mail may be sent to


This study aimed to identify factors that influenced retention in the National Institute on Drug Abuse–funded Women and Trauma Study, conducted within the Clinical Trials Network (CTN). Women (= 346) were recruited from and received treatment in 6 CTN-affiliated sites. Log-linear and logistic models were used to explore factors associated with retention. The mean number of treatment sessions attended was 6.8 (SD = 3.9). Women with more education, higher attendance at 12-step meetings, and strong therapeutic alliance between facilitator and participant had better retention rates. Significant site differences were found; the site with the highest retention rate provided child care and had the lowest average monthly intake. To retain women with histories of trauma and substance abuse in “real world” psychiatric settings, emphasis on regulating individual-level and site-related modifiable variables are crucial.