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Dual infection with Pythium insidiosum and Blastomyces dermatitidis in a dog



Sara Connolly, Department of Pathobiology, College of Veterinary Medicine, University of Illinois, 289 Small Animal Clinic, MC-004, 1008 West Hazelwood Dr. Urbana, IL 61802, USA



A 4-year-old male neutered Labrador Retriever with severe gastrointestinal signs, but no respiratory signs, was diagnosed with multifocal pyogranulomatous gastritis, enteritis, and lymphadenitis with intralesional hyphae and multifocal pyogranulomatous pneumonia with intralesional yeast. Based on cytologic evaluation, histologic examination with special stains, and immunohistochemical analysis of tissues collected antemortem or at necropsy, dual infections with Pythium insidiosum and Blastomyces dermatitidis were detected and are reported for the first time.