• Open Access

Fine-Needle Aspiration of the Spleen as an Aid in the Diagnosis of Splenomegaly

Authors

  • Deborah A. O'Keefe DVM,

    1. Department of Veterinary Clinical Sciences, The Ohio State University, Columbus, Ohio
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  • C. Guillermo Couto DVM

    1. Department of Veterinary Clinical Sciences, The Ohio State University, Columbus, Ohio
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    • 2

      Department of Veterinary Clinical Sciences, The Ohio State University, 1935 Coffey Road, Columbus, OH 43210


Abstract

Results from transabdominal fine-needle aspiration of the spleen in 28 dogs and 5 cats are reported. Splenomegaly was present in 79% of these patients, and splenic masses were present in 15%. Extramedullar hematopoiesis, the most common cytologic diagnosis, was found in 24% of the patients and was associated with a variety of diseases including immune hemolytic anemia, hemangiosarcoma, and bone marrow hypoplasia. Hematopoietic neoplasms including lymphosarcoma, plasmacytoma, myelogenous leukemia, and systemic mastocytosis were diagnosed in 24% of the patients. Other diagnoses included malignant neoplasia of undetermined cell type and lymphoreticular hyperplasia. Splenic aspirates were considered normal in 18% of the animals. Two (6%) of the aspirates contained liver tissue rather than spleen. Histologic evaluation of splenic tissue was performed in 42.5% of the patients. All cytologic diagnoses correlated well with their final histologic diagnoses. Complications from the aspiration procedure were not observed, even in thrombocytopenic patients.

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