• 1
    Britt BA. Malignant Hyperthermia: a review. In: BornGVR, FarahA., HerkenH., WelchAD, eds. Handbook of Experimental Pharmacology, Vol. 60. New York : Springer-Verlag, 1982; 547602.
  • 2
    Kruif P., Simpson WM. Possible significance of the inhibitory effect of fever on anaphylactic phenomenon. J Lab Clin Med 1940;26:125130.
  • 3
    Barlogie, Corry PM, Yip E., et al. Total-body hyperthermia with and without chemotherapy for advanced human neoplasms. Cancer Res 1979; 39:14811489.
  • 4
    Nauts HC. Historic aspects and future trends. In: OvergaardJ., ed. Hyperthermic Oncology, vol 2. London : Taylor & Francis, 1985; 199209.
  • 5
    Coley W. The treatment of malignant tumors by repeated inoculations of erysipelas with a report of 10 original cases. Am J Med Sci 1893; 105:487511.
  • 6
    MacEwen EG. Approaches to cancer therapy using biological response modifiers. Vet Clin North Am 1985; 15 (3):667688.
  • 7
    Bull JM, Lees DE, Schuette WH, et al. Immunological and physiological responses to whole-body hyperthermia. National Cancer Institute Monograph 1982; 61:177181.
  • 8
    Cavaliere R., Ciocatto EC, Giovanella BC, et al. Selective heat sensitivity of cancer cells. Cancer 1967; 20:13511381.
  • 9
    Roti JL, Laszlo A. The effects of hyperthermia on cellular macromolecules. In: UranoM., ed. Hyperthermia in Cancer Therapy. Netherlands : VNU Publications, in press.
  • 10
    Meyer JL. The clinical efficacy of localized hyperthermia. Cancer Research (suppl). 1984; 44: 4745s4751s.
  • 11
    Henle KJ, Leeper DB. Interaction of hyperthermia and radiation in CHO Cells: Recovery kinetics. Radiat Res 1976; 66:505518.
  • 12
    Rice GC, Hoy C., Schimke RT. Transient hypoxia enhances the frequency of dihydrofolate reductase gene amplification in Chinese hamster ovary cells. Proc Nat Acad Sci USA 1986; 83:59785982.
  • 13
    Wey WC. Inactivation of mammalian cells by combined hyperthermia and radiation. Front Radiat Ther Oncol 1984; 18:2940.
  • 14
    Sapareto SA, Dewey WC. Thermal dose determination in cancer therapy. Int J Radiat Oncol Biol Phys 1984; 10:787800.
  • 15
    Rheinhold HS, Endrich B. Tumor microcirculation as a target for hyperthermia. Int J Hypertherm 1986; 2:111137.
  • 16
    Dewhirst MW, Sim DA, Sapareto S., et al. Importance of minimum tumor temperature in determining early and long-term responses of spontaneous canine and feline tumors to heat and radiation. Cancer Research 1984; 44:4350.
  • 17
    Dewhirst MW, Sim DA, The utility of thermal dose as a predictor of tumor and normal tissue responses to combined radiation and hyperthermia Cancer Res (suppl) 1984; 44: 4772s4780s.
  • 18
    Thrall DE, Page RL, Dewhirst MW, et al. Temperature measurements in normal and tumor tissue in dogs undergoing whole body hyperthermia. Cancer Res 1986; 46:62296235.
  • 19
    Robins HI. Role of whole-body hyperthermia in the treatment of neoplastic disease: Its current status and future prospects. Cancer Res 1984; 44:4878s4883s.
  • 20
    Riviere JE, Page RL, Dewhirst MW, et al. Effect of hyperthermia on cisplatin pharmacokinetics in normal dogs. Int J Hypertherm, 1986; 2: 351358.
  • 21
    Hahn GM, Strande DP. Cytotoxic effects of hyperthermia and adriamycin on Chinese hamster cells. J Nat Cancer Inst 1976; 57:10631067.
  • 22
    Bates DA, Mackillop WJ. Hyperthermia, Adriamycin transport, and cytotoxicity in drug-sensitive and resistant Chinese hamster ovary cells. Cancer Res 1986; 46:54775481.
  • 23
    Bronk BV, Wilkins RJ, Regan JC. Thermal enhancement of DNA damage by an alkylating agent in human cells. Biochem Biophys Res Commun 1973; 52:10641070.
  • 24
    Hahn GM, Shiu EC. Effect of pH and elevated temperatures on the cytotoxicity of some chemotherapeutic agents on Chinese hamster cells in vitro. Cancer Res 1983; 43:57891591.
  • 25
    Hahn GM. Thermal enhancement of the actions of anticancer agents. In: HahnGM, ed. Hyperthermia and Cancer. New York : Plenum, 1982; 5585.
  • 26
    Gerweck L. Modification of cell lethality at elevated temperatures: The pH effect. Radiat Res 1977; 70:224235.
  • 27
    Kim SH, Kim JH, Hahn EW. Enhanced killing of hypoxic tumor cells by hyperthermia. Br J Radiol 1975; 48:872874.
  • 28
    Rosenthal T., Shapiro Y., Seligsohn U., et al. Disseminated intravascular coagulation in experimental heatstroke. Thromb Diath Haemorrh 1971;26:417425.
  • 29
    Kew M., Bersohn I., Seftel H. Liver damage in heatstroke. Am J Med 1979;49:192202.
  • 30
    Parks LC, Minaberry D., Smith DP, et al. Treatment of far-advanced bronchogenic carcinoma by extracorporeally induced systemic hyperthermia. J Thorac Cardiovasc Surg 1979; 78:883887.
  • 31
    Larkin JM, Edwards WS, Smith DE, et al. Systemic thermotherapy: description of a method and physiological tolerance in clinical subjects. Cancer 1977; 30:31553159.
  • 32
    Bull JM, Lees D., Schuette W., et al. Whole body hyperthermia: A phase I trial of potential adjuvant chemotherapy. Ann Int Med 1979;90:317323.
  • 33
    Henderson, Pettigrew Induction of controlled hyperthermia in treatment of cancer. Lancet 1971; 1:12751277.
  • 34
    Pomp H. Clinical application of hyperthermia in gynecological malignant tumors. In: StrefferC., vanBeuniganD., DitzelF., eds. Cancer Therapy by Hyperthermia and Radiation. Baltimore : Urban and Schwarzenberg, 1978; 326330.
  • 35
    Rheinhold HS, van der Zee J., Faithfull NS, et al. Use of Pomp-Siemens hyperthermia cabin. Natl Cancer Inst Monograph 1982;61:371375.
  • 36
    Macy DW, Macy CA, Scott RJ, et al. Physiological studies of whole-body hyperthermia of dogs. Cancer Res 1985; 45:27692773.
  • 37
    Oleson JR, Assaad A., Dewhirst MW, et al. Regional hyperthermia by magnetic induction in a beagle dog model: Analysis of thermal dosimetry. Radiat Res 1984; 98:445455.
  • 38
    Klein, MK, Dewhirst MW, Fuller DJM. Whole body hyperthermia and heat sensitizing drugs: a pilot study in canine lym-phoproliferative disease. Int J Hypertherm 1986; in press.
  • 39
    Hugander A., Robins HI, Martin P., et al. Temperature distribution during radiant heat whole body hyperthermia: experimental studies in the dog. Int J Hypertherm 1986; in press.
  • 40
    Page RL, Meyer RE, Thrall DE, et al. Cardiovascular and metabolic response of tumor-bearing dogs to whole body hyperthermia. Int J Hypertherm 1986; in press.
  • 41
    Robins HI, Dennis WH, Neville AJ, et al. Nontoxic system for 41.8 C Whole body hyperthermia: results of a phase I study using a radiant heat device. Cancer Res 1985; 45: 39373944.
  • 42
    Lees DE, Kim YD, Bull JM, et al. Anesthetic management of whole-body hyperthermia for the treatment of cancer. Anesthesiology 1980; 52:418428.
  • 43
    Cronau LH, Bourke DL, Bull JM. General anesthesia for whole-body hyperthermia. Cancer Res (suppl). 1984; 44: 4873s4877s.
  • 44
    Robins HI, Dennis WH, Martin PA, et al. Potentiation of differential hyperthermic sensitivity of AKR leukemia and normal bone marrow cells by lidocaine or thiopental. Cancer 1984; 54:28312835.
  • 45
    Meyer RE, Page RL, Thrall DE, et al. Determination of continuous atracurium infusion rate in dogs undergoing whole-body hyperthermia. Cancer Res 1986; 46:55995601.
  • 46
    Bernthal T., Week WF. Respiratory and vasomotor effect of variations in carotid body temperature. Am J Physiol 1939; 127:94105.
  • 47
    Lees DE, Kim YD, Macnamara TE. Pulmonary shunting with hyperthermia under anesthesia. Anesthesiology 1979; 51:S385.
  • 48
    Wilks D., Selker R., Weinstock E., et al. Cardiovascular effects of total body hyperthermia. Anesthesiology 1985; 63:A2.
  • 49
    Kim YD, Lake CR, Lees DE, et al. Hemodynamic and plasma catacholamine responses to hyperthermic cancer therapy in humans. Am J Physiol 1979; 237:H570574.
  • 50
    Riedel W., Iriki M., Simon E. Regional differentiation of sympathetic activity during peripheral heating and cooling in anesthetized rabbits. Pfluegers Arch 1972; 332:229247.
  • 51
    Rowell LB. Human cardiovascular adjustments to exercise and thermal stress. Physiol Rev 1974; 54:75159.
  • 52
    Walther OE, Iriki M., Simon E. Antagonistic changes in blood flow and sympathetic activity in different vascular beds following central thermal stimulation. Pfleugers Arch 1970; 319:162184.
  • 53
    Faithfull NS, Van den Berg AP, Van Rhoon GC. Cardiovascular and oxygenation changes during whole body hyperthermia. In: BicherHI, BruleyDF, eds.. Advances in Experimental Medicine and Biology, Vol. 157. New York : Plenum, 1982; 5770.
  • 54
    Lord PF, Kapp DS, Morrow D. Increased skeletal metastases of spontaneous canine osteosarcoma after fractionated systemic hyperthermia and local X-irradiation. Cancer Res 1981; 41:43314334.
  • 55
    Kapp DS, Lord PF. Tolerance of dogs to fractionated systemic hyperthermia. Nat Cancer Inst Monograph 1982; 61:391394.
  • 56
    Dewhirst MW, Connor WG. Hyperthermia. In: SlatterDH, ed.. Textbook of Small Animal Surgery. Philadelphia : WB Saunders, 1985; 24272440.