• Open Access

Medical Management of Recurrent Seizures in Dogs and Cats

Authors

  • Stephen B. Lane DVM,

    1. Department of Companion Animal and Special Species Medicine, College of Veterinary Medicine. North Carolina State University. Raleigh. North Carolina.
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  • Susan E. Bunch DVM, PhD

    Corresponding author
    1. Department of Companion Animal and Special Species Medicine, College of Veterinary Medicine. North Carolina State University. Raleigh. North Carolina.
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Department of Companion Animal and Special Species Medicine, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, NC 27606.

Abstract

The problem of recurrent seizures is a common and challenging one in veterinary medical practice. The pathophysiology and pharmacologic suppression of focal seizure activity have been studied extensively in basic research settings, yet little is known of the genesis, modulation, and termination of generalized seizures, the most common form of seizures noted to occur in companion animals. Knowledge concerning the pharmacokinetic fate of anticonvulsant drugs currently used in veterinary medicine is adequate, though prospective clinical studies of the efficacy of these drugs in the treatment of various types of seizures are lacking. This study will review the available literature regarding the pharmacology, use, and side effects of anticonvulsant drugs currently available for control of recurrent seizures in companion animals. Alternative anticonvulsant drugs will also be described. (Journal of Veterinary Internal Medicine 1990; 4:26–39)

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