Department of Clinical Studies (Philadelphia), School of Veterinary Medicine, University of Pennsylvania, 3850 Spruce St, Philadelphia, PA 19104–6010.
Spontaneous Systemic Hypertension in 24 Cats
Article first published online: 28 JUN 2008
© 1994 American College of Veterinary Internal Medicine
Journal of Veterinary Internal Medicine
Volume 8, Issue 2, pages 79–86, March 1994
How to Cite
Littman, M. P. (1994), Spontaneous Systemic Hypertension in 24 Cats. Journal of Veterinary Internal Medicine, 8: 79–86. doi: 10.1111/j.1939-1676.1994.tb03202.x
- Issue published online: 28 JUN 2008
- Article first published online: 28 JUN 2008
- Accepted July 13, 1992
Twenty-four cats with spontaneous systemic hypertension were retrospectively studied. Blood pressure (BP) was measured indirectly by the Doppler technique in 17 cats (mean systolic 219.4 ± 43.2 mm Hg) and directly by femoral arterial puncture in 15 cats (mean systolic/diastolic 233.2 ± 40.9/148.1 ± 28.7 mm Hg). All cats had bilateral retinal hemorrhages and/or detachments. Twenty cats presented because of blindness. Other presenting signs included polyuria/polydipsia, weight loss, neurological signs, and/or epistaxis. Diagnostic tests were performed to determine the presence and the cause of any secondary organ damage. Common findings included retinal hemorrhages/ detachments, low-grade systolic murmurs, cardiomegaly with left ventricular hypertrophy (LVH), small kidneys, mild azotemia, and urine specific gravity ≤ 1.020. Only 3 cats had hyperthyroidism. One cat was transiently diabetic. Necropsies on 2 cats with neurological signs showed nephrosclerosis, arteriosclerosis, and multifocal cerebral hemorrhages. Twenty cats were treated with diuretics, β-adrenergic antagonists, and/or an angiotensin converting enzyme (ACE) inhibitor. One cat was treated with methimazole only, and 1 was treated with insulin transiently. The median survival of the 24 cats was 18 months. Response to therapy did not appear to have an impact on survival time.