• 1
    Rowinsky EC, Donehower RC. Antimicrotubule agent. In: Chab-nerBA, LongoDA, eds. Cancer Chemotherapy and Biotherapy, 2nd ed. Philadelphia , PA : Lippincott-Raven; 1996: 263296.
  • 2
    Bennet JS. Mechanisms in platelet adhesion and aggregation: An update. Hosp Pract 1992;15:124140.
  • 3
    Ruggeri Z. New insights of platelet adhesion and aggregation. Semin Hematol 1994;3:229239.
  • 4
    Choi S, Simone JV, Journey LJ, et al. The mechanisms of vin-cristine-induced thrombocythemia. Blood 1972;40:965.
  • 5
    Ratzan RJ, Zueker W, Weintraub LR, et al. The mechanism responsible for vincristine (VCR) induced thrombocytopenia. Blood 1972;40:965.
  • 6
    Ahn YS, Harrington WJ, Seelman RS, et al. Vincristine therapy of idiopathic and secondary thrombocytopenias. N Engl J Med 1974; 291:375380.
  • 7
    Steinherz PG, Miller DR, Hillgartner MW, et al. Platelet dysfunction in vincristine treated patients. Br J Haematol 1976;32:439450.
  • 8
    Greene CE, Scoggin J, Thomas JE, Barsanti JE. Vincristine in the treatment of thrombocytopenia in five dogs. J Am Vet Med Assoc 1982;180:140143.
  • 9
    Mackin A. Canine immune-mediated thrombocytopenia. Part II. Compend Cont Ed Pract Vet 1995;4:515535.
  • 10
    Lewis DC, Meyers KL. Canine idiopathic thrombocytopenic purpura. J Vet Intern Med 1996;4:207218.
  • 11
    Kristensen AT, Weiss DJ, Klausner JS. Platelet dysfunction associated with immune-mediated thrombocytopenia in dogs. J Vet Intern Med 1994;8:323327.
  • 12
    George JN, Shattil SJ. The clinical importance of acquired abnormalities of platelet function. N Engl J Med 1972;1:2739.
  • 13
    Balduni CL, Grignani G, Sinigaglia FE, et al. Severe platelet dysfunction in a patient with autoantibodies against membrane gly-coproteins IIb-IIa. Hemostasis 1978;7:98104.
  • 14
    Mackin AJ, Allen DG, Johnston IB. Effects of vincristine and prednisone on platelet numbers and function in clinically normal dogs. Am J Vet Res 1995;56:100108.
  • 15
    Helfand SC, Jain NC, Paul M. Vincristine-loaded platelet therapy for idiopathic thrombocytopenia in a dog. J Am Vet Med Assoc 1984;185:224226.
  • 16
    Stemberg P, MacDonald TP, Jackson CW, et al. Disruption of microtubules in vivo by vincristine induces large membrane complexes and other cytoplasmic abnormalities in megakaryocytes and platelets of normal rats like those in human and Wistar Furth rat hereditary macrothrombocytopenias. J Cell Physiol 1995;162:86102.