• 1
    Remuzzi G., Bertani T. Pathophysiology of progressive nephrop-athies. N Engl J Med 1998;339:14481456.
  • 2
    Keane WF. Proteinuria: Its clinical importance and role in progressive renal disease. Am J Kidney Dis 2000;35:S97S105.
  • 3
    Burton C., Harris KP. The role of proteinuria in the progression of chronic renal failure. Am J Kidney Dis 1996;27:765775.
  • 4
    Keane WF, Eknoyan G. Proteinuria, albuminuria, risk, assessment, detection, elimination (PARADE): A position paper of the National Kidney Foundation. Am J Kidney Dis 1999;33:10041010.
  • 5
    Kaysen GA. Albumin metabolism in the nephrotic syndrome: The effect of dietary protein intake. Am J Kidney Dis 1988; 12: 461480.
  • 6
    Kaysen GA, Kirkpatrick WG, Couser WG. Albumin homeostasis in the nephrotic rat: Nutritional considerations. Am J Physiol 1984; 247:F192F202.
  • 7
    Rosenberg ME, Swanson JE, Thomas BL, et al. Glomerular and hormonal responses to dietary protein intake in human renal disease. Am J Physiol 1987;253:F1083F1090.
  • 8
    Kaysen GA, Jones H. Jr, Hutchison FN. High protein diets stimulate albumin synthesis at the site of albumin mRNA transcription. Kidney Int Suppl 1989;27:S168S172.
  • 9
    Kaysen GA, Jones H. Jr, Martin V., et al. A low-protein diet restricts albumin synthesis in nephrotic rats. J Clin Invest 1989; 83: 16231629.
  • 10
    Kaysen GA, Gambertoglio J., Jimenez I., et al. Effect of dietary protein intake on albumin homeostasis in nephrotic patients. Kidney Int 1986;29:572577.
  • 11
    Kaysen GA. Nutritional management of nephrotic syndrome. J Ren Nutr 1992;2:5058.
  • 12
    Finco DR, Brown SA, Brown CA, et al. Progression of chronic renal disease in the dog. J Vet Intern Med 1999;13:516528.
  • 13
    Brown SA, Crowell WA, Barsanti JA, et al. Beneficial effects of dietary mineral restriction in dogs with marked reduction of functional renal mass. J Am Soc Nephrol 1991;1:11691179.
  • 14
    Bourgoignie JJ, Gavellas G., Martinez E., et al. Glomerular function and morphology after renal mass reduction in dogs. J Lab Clin Med 1987;109:380388.
  • 15
    Polzin DJ, Osborne CA, Hayden DW, et al. Influence of reduced protein diets on morbidity, mortality, and renal function in dogs with induced chronic renal failure. Am J Vet Res 1984;45:506517.
  • 16
    Polzin DJ, Leininger JR, Osborne CA, et al. Development of renal lesions in dogs after 11/12 reduction of renal mass. Influences of dietary protein intake. Lab Invest 1988; 58: 172183.
  • 17
    Polzin DJ, Osborne CA. The importance of egg protein in reduced protein diets designed for dogs with renal failure. J Vet Intern Med 1988;2:1521.
  • 18
    Finco DR, Brown SA, Crowell WA, et al. Effects of dietary phosphorus and protein in dogs with chronic renal failure. Am J Vet Res 1992;53:22642271.
  • 19
    White JV, Finco DR, Crowell WA, et al. Effect of dietary protein on functional, morphologic, and histologic changes of the kidney during compensatory renal growth in dogs. Am J Vet Res 1991; 52: 13571365.
  • 20
    Finco DR, Brown SA, Crowell WA, et al. Effects of aging and dietary protein intake on uninephrectomized geriatric dogs. Am J Vet Res 1994;55:12821290.
  • 21
    Polzin DJ, Osborne CA, Hayden DW, et al. Effects of modified protein diets in dogs with chronic renal failure. J Am Vet Med Assoc 1983;183:980986.
  • 22
    Bovee KC, Abt DA, Kronfeld DS. The effects of dietary protein intake on renal function in dogs with experimentally reduced renal function. J Am Anim Hosp Assoc 1979;15:916.
  • 23
    Bovee KC, Kronfeld DS, Ramberg C., et al. Long-term measurement of renal function in partially nephrectomized dogs fed 56, 27, or 19% protein. Invest Urol 1979;16:378384.
  • 24
    Devaux C., Polzin DJ, Osborne CA. What role does dietary protein restriction play in the management of chronic renal failure in dogs Vet Clin North Am Small Anim Pract 1996;26:12471267.
  • 25
    Polzin DJ, Osborne CA, Adams LG. Effect of modified protein diets in dogs and cats with chronic renal failure: Current status. J Nutr 1991;121:S140S144.
  • 26
    Grauer GF, Greco DS, Getzy DM, et al. Effects of enalapril versus placebo as a treatment for canine idiopathic glomerulonephritis. J Vet Intern Med 2000;14:526533.
  • 27
    Grodecki KM, Gains MJ, Baumal R., et al. Treatment of X-linked hereditary nephritis in Samoyed dogs with angiotensin converting enzyme (ACE) inhibitor. J Comp Pathol 1997;117:209225.
  • 28
    Harvey SJ, Zheng K., Sado Y., et al. Role of distinct type IV collagen networks in glomerular development and function. Kidney Int 1998;54:18571866.
  • 29
    Valli VEO, Baumal R., Thorner P., et al. Dietary modification reduces splitting of glomerular basement membranes and delays death due to renal failure in canine X-linked hereditary nephritis. Lab Invest 1991;65:6773.
  • 30
    Jansen B., Valli VE, Thorner P., et al. Samoyed hereditary glomerulopathy: Serial, clinical and laboratory (urine, serum biochemistry and hematology) studies. Can J Vet Res 1987;51:387393.
  • 31
    Lees GE, Helman RG, Kashtan CE, et al. New form of X-linked dominant hereditary nephritis in dogs. Am J Vet Res 1999;60:373383.
  • 32
    Baumal R., Thorner P., Valli VE, et al. Renal disease in carrier female dogs with X-linked hereditary nephritis. Implications for female patients with this disease. Am J Pathol 1991; 139: 751764.
  • 33
    Kashtan C., Lees G. Skin expression of collagen IV a5 chain [a5(IV)] and proteinuria in female dogs with X-linked Alport sydrome (XLAS). J Am Soc Nephrol 1999; 10: 436A (abstract).
  • 34
    Anonymous Association of American Feed Control Officials 2003 Official Publication. Oxford , IN : Association of American Feed Control Officials Inc; 2003:155157.
  • 35
    Kleinbaum DG, Kupper LL, Muller KE. Applied Regression Analysis and Other Multivariable Methods. Boston , MA : PWS-Kent; 1988: 126138.
  • 36
    Lulich JP, Osborne CA. Interpretation of urine protein-creati-nine ratios in dogs with glomerular and nonglomerular disorders. Comp Vet Educ Pract Vet 1990;12:5972.
  • 37
    Brown SA, Brown CA, Crowell WA, et al. Beneficial effects of chronic administration of dietary omega-3 polyunsaturated fatty acids in dogs with renal insufficiency. J Lab Clin Med 1998; 131: 447455.
  • 38
    Finco DR, Brown SA, Crowell WA, et al. Effects of phosphorus/calcium-restricted and phosphorus/calcium-replete 32% protein diets in dogs with chronic renal failure. Am J Vet Res 1992; 53: 157163.
  • 39
    Dow SW, Fettman MJ, Smith KR, et al. Effects of dietary acidification and potassium depletion on acid-base balance, mineral metabolism and renal function in adult cats. J Nutr 1990;120:569578.
  • 40
    Van der MJ Bakker, Smits B., et al. Effects of source of starch on net portal flux of glucose, lactate, volatile fatty acids and amino acids in the pig. Br J Nutr 1997;78:533544.
  • 41
    Kienzle E. Effect of carbohydrates on digestion in the cat. J Nutr 1994;124:2568S2571S.
  • 42
    Gahlawat P., Sehgal S. Protein and starch digestibilities and mineral availability of products developed from potato, soy and corn flour. Plant Foods Hum Nutr 1998;52:151160.
  • 43
    Dreher ML, Dreher CJ, Berry JW. Starch digestibility of foods: A nutritional perspective. Crit Rev Food Sci Nutr 1984;20:4771.
  • 44
    Hilton J. Carbohydrates in the nutrition of the dog. Can Vet J 1990;31:128129.
  • 45
    Hegedus M. Dietary factors influencing protein utilization: A review. Acta Vet Hung 1992;40:133143.
  • 46
    Sosulski FW, Minja LA, Christensen DA. Trypsin inhibitors and nutritive value in cereals. Plant Foods Hum Nutr 1988;38:2334.
  • 47
    Turlington WH, Allee GL, Nelssen JL. Effects of protein and carbohydrate sources on digestibility and digesta flow rate in weaned pigs fed a high-fat, dry diet. J Anim Sci 1999;67:23332340.
  • 48
    Friedman M. Formation, nutritional value, and safety of D-ami-no acids. Adv Exp Med Biol 1991;289:447481.
  • 49
    Beynen AC, Kappert HJ, Yu S. Dietary lactulose decreases apparent nitrogen absorption and increases apparent calcium and magnesium absorption in healthy dogs. J Anim Physiol Anim Nutr (Berl) 2001;85:6772.
  • 50
    Finco DR, Brown SA, Brown CA, et al. Protein and calorie effects on progression of induced chronic renal failure in cats. Am J Vet Res 1998;59:575582.
  • 51
    Kleinknecht C., Laouari D., Hinglais N., et al. Role of amount and nature of carbohydrates in the course of experimental renal failure. Kidney Int 1986;30:687693.
  • 52
    Brenner BM, Meyer TW, Hostetter TH. Dietary protein intake and the progressive nature of kidney disease: The role of hemodynam-ically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation, and intrinsic renal disease. N Engl J Med 1982;307:652659.
  • 53
    Bovee KC, Kronfeld DS. Reduction of renal hemodynamics in uremic dogs fed reduced protein diets. J Am Anim Hosp Assoc 1981; 17:277285.
  • 54
    Bovee KC. Influence of dietary protein on renal function in dogs. J Nutr 1991;121:S128S139.
  • 55
    Brown SA, Finco DR. Characterization of the renal response to protein ingestion in dogs with experimentally induced renal failure. Am J Vet Res 1992;53:569573.
  • 56
    Hutchison FN, Schambelan M., Kaysen GA. Modulation of al-buminuria by dietary protein and converting enzyme inhibition. Am J Physiol 1987;253:F719F725.
  • 57
    Hutchison FN, Martin VI, Jones H. Jr., et al. Differing actions of dietary protein and enalapril on renal function and proteinuria. Am J Physiol 1990;258:F126F132.
  • 58
    Kaysen GA, Webster S., Al Bander H., et al. High-protein diets augment albuminuria in rats with Heymann nephritis by angiotensin II-dependent and -independent mechanisms. Miner Electrolyte Metab 1998;24:238245.
  • 59
    Levinsky NG, Berliner RW. The role of urea in the urine concentrating mechanism. J Clin Invest 1959;38:741748.
  • 60
    National Academy of Sciences Nutritional Research Council Nutrient Requirements of Dogs. Washington , DC : National Academy Press; 1985.
  • 61
    Kienzle E., Opitz B., Earle KE, et al. An improved method for the estimation of energy in pet foods. J Nutr 1998;128:2806S2808S.
  • 62
    Jones CH, Newstead CG, Will EJ, et al. Assessment of nutritional status in CAPD patients: Serum albumin is not a useful measure. Nephrol Dial Transplant 1997;12:14061413.
  • 63
    Shizgal HM. The effect of malnutrition on body composition. Surg Gynecol Obstet 1981;152:2226.