Renal Biopsy: A Retrospective Study of Methods and Complications in 283 Dogs and 65 Cats
Article first published online: 28 JUN 2008
© 2005 American College of Veterinary Internal Medicine
Journal of Veterinary Internal Medicine
Volume 19, Issue 6, pages 794–801, November 2005
How to Cite
Vaden, S. L., Levine, J. F., Lees, G. E., Groman, R. P., Grauer, G. F. and Forrester, S. D. (2005), Renal Biopsy: A Retrospective Study of Methods and Complications in 283 Dogs and 65 Cats. Journal of Veterinary Internal Medicine, 19: 794–801. doi: 10.1111/j.1939-1676.2005.tb02767.x
- Issue published online: 28 JUN 2008
- Article first published online: 28 JUN 2008
- Revised September 4, 2003, and March 2, 2005; Accepted May 23, 2005.
- Renaliopsy quality
Renal biopsy often is required to establish a definitive diagnosis in dogs and cats with renal disease. In this retrospective study, we determined the complications of renal biopsy as well as factors that may be associated with development of complications and procurement of adequate renal biopsy specimens in 283 dogs and 65 cats. Data extracted from medical records at 4 institutions were evaluated using logistic regression. Proteinuria was the most common indication for renal biopsy in dogs. Complications were reported in 13.4 and 18.5% of dogs and cats, respectively. The most common complication was severe hemorrhage; hydronephrosis and death were uncommon. Dogs that developed complications after renal biopsy were more likely to have been 4 to <7 years of age and >9 years, to weigh ≤5 kg, and to have serum creatinine concentrations >5 mg/dL. The majority of biopsies from both dogs (87.6%) and cats (86.2%) were considered to be of satisfactory quality. Biopsies from dogs were more likely to be of high quality if they were obtained when the patient was under general anesthesia and more likely to contain only renal cortex if they were obtained by surgery. We concluded that renal biopsy is a relatively safe procedure, with a low frequency of severe complications. Hospital practices and patient variables have the potential to impact both the quality of the specimen obtained and the rate of complications.