Presented in part as an abstract at the 26th Annual American College of Veterinary Internal Medicine Forum, Louisville, KY, June 1, 2006.
Minimally Invasive Per-Catheter Patent Ductus Arteriosus Occlusion in Dogs Using a Prototype Duct Occluder
Article first published online: 14 FEB 2008
Copyright © 2008 by the American College of Veterinary Internal Medicine
Journal of Veterinary Internal Medicine
Volume 22, Issue 1, pages 129–134, January–February 2008
How to Cite
Nguyenba, T. P. and Tobias, A. H. (2008), Minimally Invasive Per-Catheter Patent Ductus Arteriosus Occlusion in Dogs Using a Prototype Duct Occluder. Journal of Veterinary Internal Medicine, 22: 129–134. doi: 10.1111/j.1939-1676.2007.0009.x
- Issue published online: 14 FEB 2008
- Article first published online: 14 FEB 2008
- Submitted May 4, 2007; Revised June 28, 2007; Accepted August 16, 2007.
Vol. 22, Issue 3, xxviii, Article first published online: 10 JUL 2008
- Congenital anomaly;
- Heart disease;
- Multilayer nitinol mesh device;
Background: Per-catheter patent ductus arteriosus (PDA) occlusion in dogs with devices intended for humans is associated with technical difficulties, high rates of procedure abandonment, device migration, and residual ductal flow.
Hypothesis: Use of a custom-made canine duct occluder (Amplatz Canine Duct Occluder, ACDO) would be feasible in dogs of varying weights and somatotypes and effective in occluding a wide range of PDA shapes and sizes.
Animals: Eighteen client-owned dogs of various breeds with PDA. Weights ranged from 3.8 to 32.3 kg (median, 17.8 kg), and angiographic minimal ductal diameters ranged from 1.1 to 6.9 mm (median, 3.7 mm). Ductal morphologies included types IIA, IIB, and III.
Methods: Per-catheter PDA occlusion with the ACDO was performed in all dogs. Persistent or recurrent ductal flow was assessed at the end of the procedure by angiography and at 1 day, 3 months, and ≥12 months after the procedure by echocardiography.
Results: Successful ACDO placement was achieved in all 18 dogs. One dog required a 2nd procedure with a larger ACDO after the 1st device migrated to the pulmonary vasculature. Complete occlusion was confirmed in 17 of 18 dogs during the procedure, as well as at 1 day and 3 months after the procedure, and in 12 of 13 dogs evaluated at ≥12 months after the procedure.
Conclusions and Clinical Importance: Per-catheter PDA occlusion in dogs with the ACDO is feasible and effective in dogs of a wide range of weights and somatotypes and with PDAs of varying shapes and sizes.