Thromboelastographic Tracings in Retired Racing Greyhounds and in Non-Greyhound Dogs
Version of Record online: 10 MAR 2008
Copyright © 2008 by the American College of Veterinary Internal Medicine
Journal of Veterinary Internal Medicine
Volume 22, Issue 2, pages 374–379, March–April 2008
How to Cite
Vilar, P., Couto, C.G., Westendorf, N., Iazbik, C., Charske, J. and Marín, L. (2008), Thromboelastographic Tracings in Retired Racing Greyhounds and in Non-Greyhound Dogs. Journal of Veterinary Internal Medicine, 22: 374–379. doi: 10.1111/j.1939-1676.2008.0061.x
- Issue online: 10 MAR 2008
- Version of Record online: 10 MAR 2008
- Submitted June 14, 2007; Revised October 15, 2007; Accepted January 8, 2008.
- Clot kinetics;
Background: Bleeding disorders in patients with normal coagulation test results are frequently reported in Greyhounds. The purpose of this study was to compare Greyhounds to non-Greyhounds by thromboelastography (TEG).
Hypothesis: TEG parameters in Greyhounds are different from those in non-Greyhounds.
Animals: Forty-three healthy dogs (28 Greyhounds and 15 non-Greyhounds) based on the results of physical examination, CBC, activated partial thromboplastin time, prothrombin time, fibrinogen, and platelet count.
Materials and Methods: Recalcified citrated native TEGs were performed in both groups; data were compared using Student's, Mann-Whitney, and Pearson's statistical tests.
Results: In Greyhounds, mean ± SD were as follows: R-time 4.3 ± 1.7 minutes, K-time 3.8 ± 1.4 minutes, angle (α) 50.0 ± 8.0°, maximum amplitude (MA) 47.6 ± 5.6 mm, clot strength (G) 4,647 ± 1,097 dyn/cm2, and percent lysis at 60 minutes (LY60) 2.8 ± 5.0%. In the non-Greyhounds they were R-time 3.7 ± 1.6 minutes, K-time 2.5 ± 0.9 minutes, angle 59.8 ± 7.0°, MA 53.1 ± 5.6 mm, G 5,811 ± 1,256 dyn/cm2, and LY60 3.1 ± 2.5%. All parameters were significantly different between the groups, except for R-time and LY60.
Conclusion: In Greyhounds, clotting kinetics are slower and clot strength are weaker than in non-Greyhounds, supporting the increased tendency to bleed observed after minor trauma or surgical procedures in the breed. The findings may also be attributed to blood viscosity or to the concentration of citrate in the sample (ie, Greyhounds have higher hematocrit and less plasma per unit volume).