Physiology and Treatment of Retained Fetal Membranes in Cattle
Version of Record online: 28 JAN 2010
Copyright © 2010 by the American College of Veterinary Internal Medicine
Journal of Veterinary Internal Medicine
Volume 24, Issue 2, pages 261–268, March/April 2010
How to Cite
Beagley, J.C., Whitman, K.J., Baptiste, K.E. and Scherzer, J. (2010), Physiology and Treatment of Retained Fetal Membranes in Cattle. Journal of Veterinary Internal Medicine, 24: 261–268. doi: 10.1111/j.1939-1676.2010.0473.x
- Issue online: 1 MAR 2010
- Version of Record online: 28 JAN 2010
- Submitted June 6, 2009; Revised November 16, 2009; Accepted December 21, 2009.
- Placental detachment;
- Risk factors;
Retained fetal membranes (RFM) in cattle have adverse effects on fertility and production. Understanding the pathophysiology and causes of RFM is important for managing this disease. The hormonal processes that lead to normal placental separation are multifactorial and begin before parturition. A variety of risk factors, including early or induced parturition, dystocia, hormonal imbalances, and immunosuppression, can interrupt these normal processes and result in retention of the placenta. Current research does not support the efficacy of many commonly practiced treatments for RFM. Systemic administration of antibiotics can be beneficial for treating metritis after RFM, but antibiotic administration has not been shown to significantly improve future reproduction in cows with RFM. Collagenase injected into the umbilical arteries of retained placentas specifically targets the lack of placentome proteolysis and might enhance placental release. However, such therapy is costly and its benefits in terms of improving subsequent reproductive function have not been evaluated.