• Open Access

Respiratory Disease in Neonatal Cloned Calves

Authors


  • Preliminary result of this study was presented as a poster at the ACVIM Forum 2006, Seattle. This work was performed at the University Veterinary Teaching Hospital at The Faculty of Veterinary Medicine in Saint-Hyacinthe—Université de Montréal.

Corresponding author: Anne-Claire Brisville, Dre Med Vet, IPSAV, Hopital des animaux de la Ferme, Centre Hospitalier Universitaire Vétérinaire, Faculté de Médecine Vétérinaire—Saint-Hyacinthe, Université de Montréal, 3200 rue Sicotte, CP 5000, Saint-Hyacinthe, QC, Canada J2S 7C6; e-mail: anne-claire.brisville@umontreal.ca.

Abstract

Background: Numerous clinical abnormalities occur in cloned calves during the neonatal period.

Objectives: Describe respiratory diseases affecting cloned calves.

Animals: Twenty-five cloned Holstein calves.

Methods: Retrospective clinical study of the cloned calves born at the Veterinary Teaching Hospital, Saint-Hyacinthe, QC.

Results: Records of 31 cloned calves were reviewed. Twenty-five records were included. Four stillborn calves and 2 calves euthanized at birth were excluded. Twenty-two calves suffered from respiratory diseases. Nineteen calves received intranasal oxygen treatment (INO). They were tachypneic (78 breaths per minute) and 5 of them were hypoxemic (PaO2 < 55 mmHg). Two of 19 calves remained hypoxemic despite INO. Thirteen calves were weaned from INO after a median of 70 hours and were discharged at a median of 5 days of age. Nine calves required ventilatory support: 3 from birth and 6 after INO. Five were successfully weaned from the ventilator after a median of 32 hours and were discharged at a median of 8 days of age. Three calves died and 1 was euthanized because of respiratory disease. Necropsy revealed atelectasis, pulmonary congestion, and alveolar damages.

Conclusion and Clinical Importance: Respiratory disease occurs frequently in cloned calves. The most frequent abnormality is hypoxemia because of V/Q mismatch. It is possible to successfully support these calves by INO and mechanical ventilation.

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