Study abstract was presented at the 9th National Veterinary Internal Medicine Congress (Antalya, Turkey, 5–8 May 2011) as an oral presentation. The abstract was published in the proceedings
Acute-Phase Proteins, Oxidative Stress and Enzyme Activities of Blood Serum and Peritoneal Fluid in Cattle with Abomasal Displacement
Article first published online: 1 NOV 2012
Copyright © 2012 by the American College of Veterinary Internal Medicine
Journal of Veterinary Internal Medicine
Volume 26, Issue 6, pages 1470–1475, November/December 2012
Total views since publication: 25
How to Cite
Maden, M., Ozturk, A.S., Bulbul, A., Avci, G.E. and Yazar, E. (2012), Acute-Phase Proteins, Oxidative Stress and Enzyme Activities of Blood Serum and Peritoneal Fluid in Cattle with Abomasal Displacement. Journal of Veterinary Internal Medicine, 26: 1470–1475. doi: 10.1111/j.1939-1676.2012.01018.x
- Issue published online: 20 NOV 2012
- Article first published online: 1 NOV 2012
- Manuscript Accepted: 5 SEP 2012
- Manuscript Revised: 1 MAY 2012
- Manuscript Received: 1 DEC 2011
- The Scientific and Technological Research Council of Turkey. Grant Number: 108O828
- SUBAPK. Grant Number: 09401110
- Acute-phase response;
- LDA ;
Blood serum and peritoneal fluid acute-phase proteins, oxidative stress indicators, and some enzymes could be used for evaluation of abomasal tissue damage because of displacement in displaced abomasum (DA) cases.
The aim of this study was to investigate the concentrations of acute-phase proteins, oxidative stress indicators, and activities of enzymes in blood serum and peritoneal fluid in cattle with right displaced abomasum (RDA) and left displaced abomasum (LDA) and in healthy cows.
A total of 60 Holstein Friesian cows in early lactation were used, 31 with left and 9 with right displaced abomasum without volvulus diagnosis and no other postpartum disease, and 20 healthy cows as a control.
Materials and Methods
DA diagnosis in dairy cows consisted of physical examination, laboratory, and specific DA tests. Acute-phase proteins, oxidative stress indicators, and enzyme activities were measured in blood serum and peritoneal fluid.
In the RDA group, serum haptoglobin (HPG), serum amyloid A (SAA), malondialdehyde (MDA), adenosine deaminase (ADA), myeleperoxidase (MPO), aspartate aminotransferase (AST), creatine kinase (CK, creatine kinase–MB (CK-MB), and gamma-glutamyl transferase (GGT) activity increased significantly, and serum HPG, MDA, ADA, and AST concentrations increased significantly in the LDA group (P < .05). Peritoneal fluid HPG, MDA, ADA, MPO, ALP, GGT, and LDH concentrations increased significantly, whereas NO concentrations reduced significantly in the RDA group, and HPG, MDA, ADA, and TP concentrations increased significantly, whereas concentrations of NO reduced significantly in the LDA group (P < .05).
Conclusions and Clinical Importance
There are acute-phase responses, oxidative stress, and abomasal tissue damage because of displacement in DA cases. Especially, HPG, MDA, ADA, and MPO concentrations can provide specific information to help in understanding these changes.