Case was presented as part of an oral presentation at the 50th BEVA Congress in Liverpool, UK; 7th-10th Sept 2011 with abstract in proceedings (p 83).
Successful outcome in a case of equine multinodular pulmonary fibrosis (EMPF) treated with valacyclovir
Article first published online: 18 JUN 2012
© 2012 EVJ Ltd
Equine Veterinary Education
Volume 25, Issue 8, pages 389–392, August 2013
How to Cite
Schwarz, B., Schwendenwein, I. and van den Hoven, R. (2013), Successful outcome in a case of equine multinodular pulmonary fibrosis (EMPF) treated with valacyclovir. Equine Veterinary Education, 25: 389–392. doi: 10.1111/j.2042-3292.2012.00425.x
- Issue published online: 7 JUL 2013
- Article first published online: 18 JUN 2012
Equine multinodular pulmonary fibrosis (EMPF) is a progressive fibrosing interstitial lung disease, which has been associated with γ-herpesviruses. This report describes a 22-year-old Warmblood stallion diagnosed with EMPF on the basis of clinical examination, laboratory results, lung radiographs and ultrasound, lung biopsy and inclusion bodies found in macrophages of broncho-alveolar lavage fluid (BALF) as well as an identification of EHV-5 DNA by polymerase chain reaction (PCR). The horse recovered after one week of treatment with valacyclovir (40 mg/kg bwt per os q. 8 h) and is clinically healthy 2 years later. To our knowledge this is the first report describing treatment of EMPF with valacyclovir.