Present address: School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Leicestershire LE12 5RD, UK.
Delayed metastasis of ocular squamous cell carcinoma following treatment in five horses
Article first published online: 24 AUG 2012
© 2012 EVJ Ltd
Equine Veterinary Education
How to Cite
Mair, T. S., Sherlock, C. E. and Pearson, G. R. (2012), Delayed metastasis of ocular squamous cell carcinoma following treatment in five horses. Equine Veterinary Education. doi: 10.1111/j.2042-3292.2012.00435.x
- Article first published online: 24 AUG 2012
- squamous cell carcinoma;
Identification of regional and/or distant metastasis following treatment and local resolution of primary ocular squamous cell carcinoma (SCC) was observed in 5 horses. In all cases, identification of metastasis occurred at least 18 months following treatment of the primary ocular lesions. In 3 cases, invasion of blood or lymphatic vessels by neoplastic cells was identified in the excisional biopsies of the primary tumour. Two horses developed SCC at 2 or more separate sites. At the time metastases were identified, there was no evidence of local recurrence of the ocular tumour in any of the horses. These cases confirm the importance of long-term monitoring of horses for metastatic disease following treatment of ocular SCC even in the absence of local recurrence.