Andrea Deierlein is now at Department of Preventive Medicine, Mount Sinai School of Medicine, New York, USA
Gestational weight gain and predicted changes in offspring anthropometrics between early infancy and 3 years
Article first published online: 10 FEB 2012
© 2012 The Authors. Pediatric Obesity © 2012 International Association for the Study of Obesity
Volume 7, Issue 2, pages 134–142, April 2012
How to Cite
Deierlein, A. L., Siega-Riz, A. M., Herring, A. H., Adair, L. S. and Daniels, J. L. (2012), Gestational weight gain and predicted changes in offspring anthropometrics between early infancy and 3 years. Pediatric Obesity, 7: 134–142. doi: 10.1111/j.2047-6310.2011.00025.x
- Issue published online: 13 MAR 2012
- Article first published online: 10 FEB 2012
- Manuscript Accepted: 22 NOV 2011
- Manuscript Revised: 2 NOV 2011
- Manuscript Received: 13 JUL 2011
- National Institutes of Health. Grant Numbers: HD37584, HD39373
- National Institute of Diabetes and Digestive and Kidney Diseases. Grant Numbers: DK61981, DK56350
- gestational weight gain;
To determine how gestational weight gain (GWG), categorized using the 2009 Institute of Medicine recommendations, relates to changes in offspring weight-for-age (WAZ), length-for-age (LAZ) and weight-for-length z-scores (WLZ) between early infancy and 3 years.
Women with singleton infants were recruited from the third cohort of the Pregnancy, Infection, and Nutrition Study (2001–2005). Term infants with at least one weight or length measurement during the study period were included (n = 476). Multivariable linear mixed effects regression models estimated longitudinal changes in WAZ, LAZ and WLZ associated with GWG.
In early infancy, compared with infants of women with adequate weight gain, those of women with excessive weight gains had higher WAZ, LAZ and WLZ. Excessive GWG ≥ 200% of the recommended amount was associated with faster rates of change in WAZ and LAZ and noticeably higher predicted mean WAZ and WLZ that persisted across the study period.
GWG is associated with significant differences in offspring anthropometrics in early infancy that persisted to 3 years of age. More longitudinal studies that utilize maternal and paediatric body composition measures are necessary to understand the nature of this association.