Provided equal last author contributions to this paper.
Associations between aggressive behaviour scores and cardiovascular risk factors in childhood
Article first published online: 18 APR 2012
© 2012 The Authors. Pediatric Obesity © 2012 International Association for the Study of Obesity
Volume 7, Issue 4, pages 319–328, August 2012
How to Cite
Louise, S., Warrington, N. M., McCaskie, P. A., Oddy, W. H., Zubrick, S. R., Hands, B., Mori, T. A., Briollais, L., Silburn, S., Palmer, L. J., Mattes, E. and Beilin, L. J. (2012), Associations between aggressive behaviour scores and cardiovascular risk factors in childhood. Pediatric Obesity, 7: 319–328. doi: 10.1111/j.2047-6310.2012.00047.x
- Issue published online: 6 JUL 2012
- Article first published online: 18 APR 2012
- Manuscript Accepted: 10 JAN 2012
- Manuscript Revised: 30 NOV 2011
- Manuscript Received: 24 SEP 2011
- Telethon Institute for Child Health Research
- The University of Western Australia
- King Edward Memorial Hospital
- University of Western Australia
- cardiovascular disease;
- Raine study;
- risk factors
To examine the influence of aggressive behaviour scores on cardiovascular disease (CVD) risk factors throughout childhood.
This study utilized cross-sectional and longitudinal data from the Western Australian Pregnancy Cohort (Raine) Study (n = 2900). Aggressive behaviour scores were derived from the Child Behavior Checklist/4–18(CBCL), Youth Self-Report/11–18 (YSR) and Teacher Report Form/6–18 (TRF). CVD risk factors included body mass index (BMI), blood pressure, fasting lipids and homeostasis model of insulin resistance (HOMA-IR).
Girls with higher aggressive behaviour scores had higher BMI from 10 years of age (P ≤ 0.001), higher BMI trajectories throughout childhood (P = 0.0003) and at 14 years higher HOMA-IR (P = 0.008). At the 14-year survey, this equated to a difference of 1.7 kg/m2 in the predicted BMI between the extreme CBCL scores in girls (top 5% (CBCL ≥ 17) vs. CBCL score = 0). Boys with higher aggressive behaviour scores had higher BMI at 5 years (P = 0.002), lower diastolic pressure at 14 years (P = 0.002) and lower systolic blood pressure trajectories throughout childhood (P = 0.016).
Aggressive behaviour influences BMI from early childhood in girls but not boys. If this association is causal, childhood offers the opportunity for early behavioural intervention for obesity prevention.