What is already known about this subject
- Childhood obesity plays a fundamental role in the development of cardiovascular disease (CVD) and type 2 diabetes in adulthood.
- Clinical guidelines for the early management of CVD in children are poorly defined. Traditional cholesterol biomarkers such as low-density lipoprotein cholesterol usually fall within the normal range in pre-pubertal children with obesity.
- Remnant lipoproteins are overproduced by the intestine during obesity and type-2 diabetes in adults and are an independent risk factor for CVD.