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Table S1. Genotype frequencies for controls were in Hardy-Weinberg equilibrium.

Table S2. Univariate analysis for the 109 SNPs within the genes FTO SEC16B, BDNF, ETV5, SH2B1, GNPDA2, LYPLAL1, MSRA, TFAP2, KCTD15, MTCH2 and NEGR1, genotyped in the case/control study.

Table S3. Discovery sample include our series of cases and controls. Validation sample is the INMA cohort. Five of the six SNPS from the previous analysis were available in the imputed data. The quality of imputation was high, with score ranging from 0.9 to 1.0.

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