The Partnership for Citrus Worker Health is a coalition formed by researchers at the University of South Florida Prevention Research Center and the Farm Worker Association of Florida. With the help of a community advisory board composed of agricultural laborers, public health professionals and agricultural employers, the project conducted research and designed an intervention that focused on eye safety among citrus harvesters. This case study demonstrates the successful use of a variety of participatory techniques and approaches, including social marketing, focus group research, community health workers, and quantitative measures of behavior change. The case also demonstrates how diverse stakeholders, including the researchers, the community advisory board and the target audience, collaborated to define problems and adopt solutions that make the agricultural workplace safer and improve conditions in the community. However, the way in which agricultural production utilizes migrant labor ultimately sets limits to the success of such collaborative approaches.