The National Institutes of Health (NIH) has a number of mechanisms available to support research, research training and research career development. The various institutes, centers and special offices within the NIH have, as part of their missions, a diverse array of basic and clinical research goals. Much of the scientific spectrum of reproductive immunology, however, falls within the mission of the National Institute of Child Health and Human Development (NICHD). There have been a number of recent innovations in the preparation, review and funding of NIH grant applications. Specific opportunities, such as fellowships, career awards, and new investigator status, are available for investigators at different career stages. A wealth of information is available on the NIH website at www.nih.gov. NIH staff are available to answer your questions and to provide administrative guidance in preparing grant applications.