Burnout is a prevalent problem in advanced market economies, and recent economic downturns have created conditions that increase the likelihood of burnout within organizations. This present paper addresses the current absence of research in the scientific literature on how macro-level factors may affect burnout. We propose a conceptual model of burnout, which introduces the macro environment, organization behaviors, and both individual and organizational stressors that all contribute to burnout. Furthermore, we review the burnout literature and provide a multilevel preventive approach for dealing with burnout. Trends and previous findings in the literature support the proposed conceptual model.