Cross-talk between probiotic lactobacilli and host immune system

Authors

  • T.S. Kemgang,

    1. Department of Animal Biochemistry, National Dairy Research Institute, Karnal, Haryana, India
    2. Department of Food Science/Nutrition, National School of AgroIndustrial Sciences, University of Ngaoundere, Ngaoundere, Adamaoua, Cameroon
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  • S. Kapila,

    Corresponding author
    1. Department of Animal Biochemistry, National Dairy Research Institute, Karnal, Haryana, India
    • Correspondence

      Suman Kapila, National Dairy Research Institute, Animal Biochemistry Division, Immunochemistry Laboratory, 132001 Karnal, India. E-mail: suman_ndri@yahoo.com

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  • V.P. Shanmugam,

    1. Department of Animal Biochemistry, National Dairy Research Institute, Karnal, Haryana, India
    2. Department of Veterinary Biochemistry, Rajiv Gandhi Institute of Veterinary Education and Research, Kurumbapet, Puducherry, India
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  • R. Kapila

    1. Department of Animal Biochemistry, National Dairy Research Institute, Karnal, Haryana, India
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Summary

The mechanism by which probiotic lactobacilli affect the immune system is strain specific. As the immune system is a multicompartmental system, each strain has its way to interact with it and induce a visible and quantifiable effect. This review summarizes the interplay existing between the host immune system and probiotic lactobacilli, that is, with emphasis on lactobacilli as a prototype probiotic genus. Several aspects including the bacterial-host cross-talk with the mucosal and systemic immune system are presented, as well as short sections on the competing effect towards pathogenic bacteria and their uses as delivery vehicle for antigens.

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