This study examined the effects of locus of control, self-esteem, and organizational climate on psychological empowerment in a sample of Chinese teachers. Participants were 1,272 Chinese teachers (460 men and 821 women) residing in six provinces in China. Results indicated that self-esteem was a positive predictor of psychological empowerment. Several dimensions of organizational climate, namely professional communication, decision-making, appraisal and recognition, supportive leadership, and professional growth, were also positive predictors of teachers’ psychological empowerment. Locus of control, although related to psychological empowerment, had no predictive effects when other factors related to empowerment were considered.