The study was supported by the Heart and Stroke Foundation of Ontario (T6730). Dr. Krahn is a Career Investigator of the Heart and Stroke Foundation of Ontario (CI6498).
Ventricular Fibrillation Induced by Spontaneous Hypothermia in a Patient with Early Repolarization Syndrome
Article first published online: 9 NOV 2012
© 2012 Wiley Periodicals, Inc.
Journal of Cardiovascular Electrophysiology
Volume 24, Issue 5, pages 586–588, May 2013
How to Cite
FEDERMAN, N. J., MECHULAN, A., KLEIN, G. J. and KRAHN, A. D. (2013), Ventricular Fibrillation Induced by Spontaneous Hypothermia in a Patient with Early Repolarization Syndrome. Journal of Cardiovascular Electrophysiology, 24: 586–588. doi: 10.1111/jce.12030
- Issue published online: 26 APR 2013
- Article first published online: 9 NOV 2012
- Accepted manuscript online: 10 OCT 2012 04:57AM EST
- Manuscript Accepted: 7 SEP 2012
- Manuscript Revised: 3 SEP 2012
- Manuscript Received: 2 AUG 2012
- Heart and Stroke Foundation of Ontario. Grant Number: T6730
- Heart and Stroke Foundation of Ontario. Grant Number: CI6498
- cardiac arrest;
- early repolarization syndrome;
- J wave;
- ventricular fibrillation
Hypothermia and Early Repolarization Syndrome
The early repolarization (ER) pattern on ECG was originally described in the context of hypothermia.
We present the case of a 34-year-old male with cardiac arrest in the context of spontaneous hypothalamic mediated thermal dysregulation after intracranial hemorrhage. Ventricular fibrillation with a marked ER pattern recurred with therapeutic hypothermia. Spontaneous hypothermia due to hypothalamic dysregulation was observed to enhance the amplitude of the ER pattern and was contemporaneous with recurrent ventricular fibrillation during follow-up.
Hypothermia is an important trigger of VF in the setting of early repolarization syndrome, and warrants assessment as an environmental trigger of spontaneous events. (J Cardiovasc Electrophysiol, Vol. 24, pp. 586–588, May 2013)