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Effects of Open-Irrigated Radiofrequency Ablation Catheter Design on Lesion Formation and Complications: In Vitro Comparison of 6 Different Devices

Authors

  • JOSE M. GUERRA M.D., Ph.D.,

    Corresponding author
    • Department of Cardiology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Institut de Recerca HSCSP-IIB Sant Pau, Barcelona, Spain
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  • ESTHER JORGE D.V.M, Ph.D.,

    1. Department of Cardiology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Institut de Recerca HSCSP-IIB Sant Pau, Barcelona, Spain
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  • SILVIA RAGA B.Sc.,

    1. Department of Cardiology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Institut de Recerca HSCSP-IIB Sant Pau, Barcelona, Spain
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  • CAROLINA GÁLVEZ-MONTÓN D.V.M, Ph.D.,

    1. Department of Cardiology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Institut de Recerca HSCSP-IIB Sant Pau, Barcelona, Spain
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  • CONCEPCIÓN ALONSO-MARTÍN M.D.,

    1. Department of Cardiology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Institut de Recerca HSCSP-IIB Sant Pau, Barcelona, Spain
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  • ENRIQUE RODRÍGUEZ-FONT M.D.,

    1. Department of Cardiology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Institut de Recerca HSCSP-IIB Sant Pau, Barcelona, Spain
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  • JUAN CINCA M.D., Ph.D.,

    1. Department of Cardiology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Institut de Recerca HSCSP-IIB Sant Pau, Barcelona, Spain
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  • XAVIER VIÑOLAS M.D.

    1. Department of Cardiology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Institut de Recerca HSCSP-IIB Sant Pau, Barcelona, Spain
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  • Presented in part at the Heart Rhythm Society 33rd Annual Scientific Sessions, Boston, MA, 2012, and previously published in abstract form (Heart Rhythm 2012;9:S196).

  • Supported in part by a nonconditioned research grant from Boston Scientific Europe.

  • Dr. Guerra reports compensation for participation on a speaker's bureau for Boston Scientific. Other authors: No disclosures.

Address for correspondence: Jose M. Guerra, M.D., Ph.D., Electrophysiology Unit, Department of Cardiology, Hospital de la Santa Creu i Sant Pau, Sant Antoni M Claret, 167 08025 Barcelona, Spain. Fax: +34 93 5565603; E-mail: jguerra@santpau.cat

In Vitro Comparison of Open-Irrigated Catheters

Introduction

Open-irrigated radiofrequency ablation catheters with slight differences in tip architecture are widely used, although limited comparative data are available. The purpose of this study was to compare the lesion size and potential complications produced by commercially available open-irrigated catheters in an in vitro porcine heart model.

Methods and Results

Six catheters were tested (Biosense Webster Thermocool, Boston Scientific Open irrigated, St. Jude CoolPath, St. Jude CoolPath Duo, Biosense Webster Thermocool SF, St. Jude Cool Flex) at 20 and 35 W power-control, under 2 different blood flows (0.1 and 0.5 m/s) and at 2 target durations (30 and 60 seconds). A total of 601 lesions were made in 26 in vitro preparations. The tip temperature profile showed significant differences between the catheters (P < 0.001) with the Thermocool SF registering the lowest. Only the surface diameter and the depth at maximum diameter of the lesion were influenced by the design of the ablation electrode. The lesion volume did not show significant differences between catheters for any power, application duration or blood flow condition. Char and pops occurred more often at 35 W with only slight differences between the catheters.

Conclusions

Tip design of the 6 different irrigated catheters does not affect the lesion total volume, although a slight difference in lesion geometry in terms of surface diameter and depth at maximum diameter is present. The catheters show a slight different in vitro safety profile

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