Is Isolated Systolic Hypertension Worse Than Combined Systolic/Diastolic Hypertension?
Article first published online: 9 OCT 2012
© 2012 Wiley Periodicals, Inc.
The Journal of Clinical Hypertension
Volume 14, Issue 11, pages 808–809, November 2012
How to Cite
Ma, Y., Yabluchanskiy, A., Lindsey, M. L. and Chilton, R. J. (2012), Is Isolated Systolic Hypertension Worse Than Combined Systolic/Diastolic Hypertension?. The Journal of Clinical Hypertension, 14: 808–809. doi: 10.1111/jch.12011
- Issue published online: 5 NOV 2012
- Article first published online: 9 OCT 2012
- Manuscript received: July 30, 2012; accepted: July 31, 2012
J Clin Hypertens (Greenwich). 2012;14:808–809. ©2012 Wiley Periodicals, Inc.
New developments in cardiovascular translational sciences have significantly advanced our understanding of the endovascular biology of blood pressure. Reductions in vascular elasticity and vessel compliance of conduit arteries are key components of both ISH and SDH. Vascular changes from the matrix metalloproteinase family of enzymes are involved in arterial wall remodeling and vascular stiffness. This new translational information helps further our understanding of both ISH and SDH.