Recurrent Hypertensive Cerebral Hemorrhages in a Boy Caused by a Reninoma: Rare Manifestations and Distinctive Electron Microscopy Findings
Article first published online: 3 OCT 2012
© 2012 Wiley Periodicals, Inc.
The Journal of Clinical Hypertension
Volume 14, Issue 11, pages 802–805, November 2012
How to Cite
Mao, J., Wang, Z., Wu, X., Dai, W. and Tong, A. (2012), Recurrent Hypertensive Cerebral Hemorrhages in a Boy Caused by a Reninoma: Rare Manifestations and Distinctive Electron Microscopy Findings. The Journal of Clinical Hypertension, 14: 802–805. doi: 10.1111/jch.12015
- Issue published online: 5 NOV 2012
- Article first published online: 3 OCT 2012
- Manuscript received: July 20, 2012; revised: August 6, 2012; accepted: August 14, 2012
J Clin Hypertens (Greenwich). 2012;14:802–805. ©2012 Wiley Periodicals, Inc.
Recurrent cerebral hemorrhages caused by hypertension secondary to reninoma are extremely rare in children. Because of its detrimental effects on children’s health, the importance of early diagnosis of and treatment for reninoma should be emphasized. Here, the authors present a 10-year-old boy with intermittent headaches and neurologic deficiency symptoms caused by hypertension. A reninoma in the right kidney was detected and successfully treated with laparoscopic partial nephrectomy. Two cell types were revealed in the tumor tissue under electron microscopy: renin secreting tumor cells and mast cells. This rare case expands our knowledge of hypertension in children and provides direct evidence that mast cells may infiltrate reninoma.