These authors equally contributed to this work.
M2 receptor activation inhibits cell cycle progression and survival in human glioblastoma cells
Article first published online: 14 MAR 2013
© 2013 The Authors Journal of Cellular and Molecular Medicine Published by Foundation for Cellular and Molecular Medicine/Blackwell Publishing Ltd
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Journal of Cellular and Molecular Medicine
Volume 17, Issue 4, pages 552–566, April 2013
How to Cite
Ferretti, M., Fabbiano, C., Bari, M. D., Conte, C., Castigli, E., Sciaccaluga, M., Ponti, D., Ruggieri, P., Raco, A., Ricordy, R., Calogero, A. and Tata, A. M. (2013), M2 receptor activation inhibits cell cycle progression and survival in human glioblastoma cells. Journal of Cellular and Molecular Medicine, 17: 552–566. doi: 10.1111/jcmm.12038
- Issue published online: 28 APR 2013
- Article first published online: 14 MAR 2013
- Manuscript Accepted: 15 JAN 2013
- Manuscript Received: 23 JUL 2012
- MIUR-PRIN. Grant Number: 2007L7BHK8-002
- Fari. Grant Number: C26I10LH54
|jcmm12038-sup-0001-FigS1.tif||image/tif||1559K||Figure S1 Immunohistochemistry of M2 receptors in fresh glioma biopsy. The arrows indicated the positive cells (1000X).|
|jcmm12038-sup-0002-FigS2.tif||image/tif||2718K||Figure S2 Immunocytochemistry analysis of M2 receptor in U251 cells after siRNA transfection. (A) Control (in absence of siRNA). The red arrows indicate the positive cells (150x). (B) Hoechst staining of U251 siRNA transfected cells; the blue arrows indicate the nuclei of cells that are completely negative for M2 staining in Fig. C (150x). (C) M2 staining in U251 siRNA transfected cells (150x). The immunostaining appears decreased respect to the control (A); some spots of fluorescence appear on the plasma membrane of the cells, as evident in the frame showing higher magnification of one cell (300x).|
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