• 1
    Vincent A, Herman J, Schulick R, et al. Pancreatic cancer. Lancet. 2011; 378: 60720.
  • 2
    Raimondi S, Maisonneuve P, Lowenfels AB. Epidemiology of pancreatic cancer: an overview. Nat Rev Gastroenterol Hepatol. 2009; 6: 699708.
  • 3
    Lonardo E, Hermann PC, Heeschen C. Pancreatic cancer stem cells – update and future perspectives. Mol Oncol. 2010; 4: 43142.
  • 4
    Al-Hajj M, Wicha MS, Benito-Hernandez A, et al. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci. 2003; 100: 39838.
  • 5
    Ricci-Vitiani L, Lombardi DG, Pilozzi E, et al. Identification and expansion of human colon-cancer-initiating cells. Nature. 2007; 445: 1115.
  • 6
    Houghton J, Stoicov C, Nomura S, et al. Gastric cancer originating from bone marrow-derived cells. Science. 2004; 306: 156871.
  • 7
    Varon C, Dubus P, Mazurier F, et al. Helicobacter pylori infection recruits bone marrow-derived cells that participate in gastric preneoplasia in mice. Gastroenterology. 2012; 142: 28191.
  • 8
    Pan JJ, Oh SH, Lee WC, et al. Bone marrow-derived progenitor cells could modulate pancreatic cancer tumorigenesis via peritumoral microenvironment in a rat model. Oncol Res. 2009; 17: 33945.
  • 9
    Ratajczak MZ, Liu R, Marlicz W, et al. Identification of very small embryonic/epiblast-like stem cells (VSELs) circulating in peripheral blood during organ/tissue injuries. Methods Cell Biol. 2011; 103: 3154.
  • 10
    Kucia M, Halasa M, Wysoczynski M, et al. Morphological and molecular characterization of novel population of CXCR4+SSEA-4+Oct-4+ very small embryonic-like cells purified from human cord blood: preliminary report. Leukemia. 2007; 21: 297303.
  • 11
    Shin DM, Zuba-Surma EK, Wu W, et al. Novel epigenetic mechanisms that control pluripotency and quiescence of adult bone marrow-derived Oct-4(+) very small embryonic-like stem cells. Leukemia. 2009; 23: 204251.
  • 12
    Ratajczak MZ, Shin DM, Kucia M. Very small embryonic/epiblast-like stem cells: a missing link to support the germ line hypothesis of cancer development? Am J Pathol. 2009; 174: 198592.
  • 13
    Ratajczak MZ, Lee H, Wysoczynski M, et al. Novel insight into stem cell mobilization-plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow, and its level in peripheral blood increases during mobilization due to activation of the complement cascade/membrane attack complex. Leukemia. 2010; 24: 97685.
  • 14
    Golan K, Vagima Y, Ludin A, et al. S1P promotes murine progenitor cell egress and mobilization via S1P1 mediated ROS signaling and SDF-1 release. Blood. 2012; 119: 247888.
  • 15
    Wojakowski W, Tendera M, Kucia M, et al. Mobilization of bone marrow-derived Oct4+ SSEA-4+ very small embryonic-like stem cells in patients with acute myocardial infarction. J Am Coll Cardiol. 2009; 53: 19.
  • 16
    Marlicz W, Zuba-Surma E, Kucia M, et al. Various types of stem cells, including a population of very small embryonic-like stem cells, are mobilized into peripheral blood in patients with Crohn's disease. Inflamm Bowel Dis. 2012; 18: 171122.
  • 17
    Dołęgowska B, Błogowski W, Chlubek D. The effect in vitro of glucose on erythrocyte resistance to hemolysis. Ann Acad Med Stetin. 2006; 52: 258.
  • 18
    Dołęgowska B, Stepniewska J, Ciechanowski K, et al. Does glucose in dialysis fluid protect erythrocytes in patients with chronic renal failure? Blood Purif. 2007; 25: 4229.
  • 19
    Błogowski W, Serwin K, Sałata D, et al. Plasma and adipose tissue levels of selected growth/inhibitory factors, proteolytic enzymes and sphingosine-1-phosphate in humans. Eur J Inflamm. 2012; 3: 27988.
  • 20
    Lee HM, Wu W, Wysoczynski M, et al. Impaired mobilization of hematopoietic stem/progenitor cells in C5-deficient mice supports the pivotal involvement of innate immunity in this process and reveals novel promobilization effects of granulocytes. Leukemia. 2009; 23: 205262.
  • 21
    Scarlett CJ, Colvin EK, Pinese M, et al. Recruitment and activation of pancreatic stellate cells from the bone marrow in pancreatic cancer: a model of tumor-host interaction. PLoS ONE. 2011; 6: e26088.
  • 22
    Jung KH, Song SU, Yi T, et al. Human bone marrow-derived clonal mesenchymal stem cells inhibit inflammation and reduce acute pancreatitis in mice. Gastroenterology. 2011; 140: 9981008.
  • 23
    Shankar S, Nall D, Tang S-N, et al. Resveratol inhibits pancreatic cancer stem cell characteristics in human and KrasG12D transgenic mice by inhibiting pluripotency maintaining factors and epithelial-mesenchymal transition. PLoS ONE. 2011; 6: e16530.
  • 24
    Gao Z, Wang X, Wu K, et al. Pancreatic stellate cells increase the invasion of human pancreatic cancer cells through the stromal cell-derived factor-1/CXCR4 axis. Pancreatology. 2010; 10: 18693.
  • 25
    Koshiba T, Hosotani R, Miyamoto Y, et al. Expression of stromal cell-derived factor 1 and CXCR4 ligand receptor system in pancreatic cancer: a possible role for tumor progression. Clin Cancer Res. 2000; 6: 35305.
  • 26
    Vizio B, Novarino A, Giacobino A, et al. Pilot study to relate clinical outcome in pancreatic carcinoma and angiogenic plasma factors/circulating mature/progenitor endothelial cells: preliminary results. Cancer Sci. 2010; 101: 244854.
  • 27
    Cho K, Matsuda Y, Ueda J, et al. Keratinocyte growth factor induces matrix metalloproteinase-9 expression and correlates with venous invasion in pancreatic cancer. Int J Oncol. 2012; 40: 10408.
  • 28
    Orr FW, Delikatny EJ, Mokashi S, et al. Detection of a complement-derived chemotactic factor for tumor cells in human inflammatory and neoplastic effusions. Am J Pathol. 1983; 110: 417.
  • 29
    Bendall L, Juarez JG, Harun N, et al. Sphingosine-1-phosphate facilitates trafficking of hematopoietic stem cells and their mobilization by CXCR4 antagonists in mice. Exp Hematol. 2011; 39: S97.