These authors contributed equally to this paper.
PMC, a potent hydrophilic α-tocopherol derivative, inhibits NF-κB activation via PP2A but not IκBα-dependent signals in vascular smooth muscle cells
Article first published online: 13 APR 2014
© 2014 The Authors. Journal of Cellular and Molecular Medicine published by John Wiley & Sons Ltd and Foundation for Cellular and Molecular Medicine.
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Journal of Cellular and Molecular Medicine
Volume 18, Issue 7, pages 1278–1289, July 2014
How to Cite
Hsieh, C.-Y., Hsiao, G., Hsu, M.-J., Wang, Y.-H. and Sheu, J.-R. (2014), PMC, a potent hydrophilic α-tocopherol derivative, inhibits NF-κB activation via PP2A but not IκBα-dependent signals in vascular smooth muscle cells. Journal of Cellular and Molecular Medicine, 18: 1278–1289. doi: 10.1111/jcmm.12277
- Issue published online: 30 JUL 2014
- Article first published online: 13 APR 2014
- Manuscript Accepted: 11 FEB 2014
- Manuscript Received: 30 SEP 2013
- National Science Council, Taiwan. Grant Numbers: NSC99-2811-B-038-019, NSC100-2811-B-038-015, NSC101-2811-B-038-019, NSC100-2320-B-038-021-MY3
Figure S1 The role of NADPH oxidase in LPS/IFN-γ-induced ROS production in VSMCs.
Figure S2 Effects of PMC on IκBα degradation and p65 phosphorylation in TNF-α-activated VSMCs.
Figure S3 Effects of PMC on iNOS expression in H2O2-activated VSMCs.
Figure S4 Evaluation of PP2A activity in H2O2-treated vascular smooth muscle cells (VSMCs).
|jcmm12277-sup-0003-FigS5.tiff||TIFF image||291K||Figure S5 Effects of N-acetylcysteine (NAC) on p65 phosphorylation and dimethyl-PP2A (DM-PP2A) expression in LPS/IFN-γ-activated VSMCs.|
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