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jcmm12286-sup-0001-FigS1.tifimage/tif25KFigure S1 Curcumin reduces liver/body weight ratio in rat fibrotic liver caused by CCl4. Rats were grouped: group 1, vehicle control (no CCl4, no treatment); group 2, model group (with CCl4, no treatment); group 3, curcumin-treated group (100 mg/kg + CCl4); group 4, curcumin-treated group (200 mg/kg + CCl4); group 5, curcumin-treated group (400 mg/kg + CCl4). #P < 0.05 versus group 1, *P < 0.05 versus group 2, n = 6.
jcmm12286-sup-0002-FigS2.tifimage/tif57KFigure S2 Effects of curcumin (A), imatinib (B), U0126 (C) and rapamycin (D) on cell viability in HSCs. HSCs were treated with DMSO (0.02%, w/v) and compounds at indicated concentrations for 24 hrs. Cell viability was evaluated by MTS assay. For the statistics of each panel in this figure, *P < 0.05 versus control.
jcmm12286-sup-0003-FigS3.tifimage/tif38KFigure S3 Effects of Y15 (A) and fasudil (B) on cell viability in HSCs. HSCs were treated with DMSO (0.02%, w/v) and compounds at indicated concentrations for 24 hrs. Cell viability was evaluated by MTS assay. For the statistics of each panel in this figure, *P < 0.05 versus control.

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