Conflict of interest statement: No conflict of interest.
Psychiatric outcomes at age seven for very preterm children: rates and predictors
Article first published online: 24 JAN 2013
© 2013 The Authors. Journal of Child Psychology and Psychiatry © 2013 Association for Child and Adolescent Mental Health.
Journal of Child Psychology and Psychiatry
Volume 54, Issue 7, pages 772–779, July 2013
How to Cite
Treyvaud, K., Ure, A., Doyle, L. W., Lee, K. J., Rogers, C. E., Kidokoro, H., Inder, T. E. and Anderson, P. J. (2013), Psychiatric outcomes at age seven for very preterm children: rates and predictors. Journal of Child Psychology and Psychiatry, 54: 772–779. doi: 10.1111/jcpp.12040
- Issue published online: 24 JUN 2013
- Article first published online: 24 JAN 2013
- Accepted for publication: 5 November 2012 ,
- psychiatric disorder;
- brain abnormality;
- mental health
Background: Uncertainty remains about the rate of specific psychiatric disorders and associated predictive factors for very preterm (VPT) children. The aims of this study were to document rates of psychiatric disorders in VPT children aged 7 years compared with term born children, and to examine potential predictive factors for psychiatric diagnoses in VPT children.
Methods: Participants were 177 VPT and 65 term born children. Perinatal medical data were collected, which included brain abnormalities detected using magnetic resonance imaging. The Infant-Toddler Social-Emotional Assessment (ITSEA) and Strengths and Difficulties Questionnaire (SDQ) were administered at 2 and 5 years respectively. At 7 years of age, the Developmental and Well-being Assessment (DAWBA) was used to indicate psychiatric diagnoses.
Results: Compared with term born children, VPT children had three times the odds of meeting criteria for any psychiatric diagnosis at age 7 years (odds ratio 3.03; 95% confidence interval 1.23, 7.47, p = .02). The most common diagnoses were anxiety disorders (11% VPT, 8% term), attention-deficit/hyperactivity disorder (10% VPT, 3% term) and autism spectrum disorder (4.5% VPT, 0% term). For VPT children, those with severe global brain abnormalities (p = .02), those who displayed social-emotional problems at age 5 (p = .000) and those with higher social risk at age 7 (p = .001) were more likely to meet criteria for a psychiatric illness at age 7.
Conclusions: Compared with term born children, VPT children have higher rates of psychiatric diagnoses at early school age, predicted by neonatal brain abnormalities, prior social-emotional problems and social factors.