• Open Access

Algorithm for dermocosmetic use in the management of cutaneous side-effects associated with targeted therapy in oncology


  • Conflict of interest

    • All the signing authors except R.J. Bensadoun are members of the scientific advisory board of La Roche-Posay Laboratoire Pharmaceutique, France. S. Seité and A. Rougier are employees of this company.
  • Funding sources

    • This algorithm was funded by La Roche-Posay Laboratoire Pharmaceutique, France. All members of the expert panel received honoraria for their contribution.

Correspondence: S. Seité. E-mail: sophie.seite@loreal.com


Currently, numerous patients who receive targeted chemotherapy for cancer suffer from disabling skin reactions due to cutaneous toxicity, which is a significant problem for an increasing number of patients and their treating physicians. In addition, using inappropriate personal hygiene products often worsens these otherwise manageable side-effects. Cosmetic products for personal hygiene and lesion camouflage are part of a patients’ well-being and an increasing number of physicians feel that they do not have adequate information to provide effective advice on concomitant cosmetic therapy. Although ample information is available in the literature on pharmaceutical treatment for cutaneous side-effects of chemotherapy, little is available for the concomitant use of dermatological skin-care products with medical treatments. The objective of this consensus study is to provide an algorithm for the appropriate use of dermatological cosmetics in the management of cutaneous toxicities associated with targeted chemotherapy such as epidermal growth factor receptor inhibitors and other monoclonal antibodies. These guidelines were developed by a French and German expert group of dermatologists and an oncologist for oncologists and primary care physicians who manage oncology patients. The information in this report is based on published data and the expert group's opinion. Due to the current lack of clinical evidence, only a review of published recommendations including suggestions for concomitant cosmetic use was conducted.