Conflict of interest
Atopic dermatitis burden scale: creation of a specific burden questionnaire for families
Article first published online: 16 MAY 2013
© 2013 European Academy of Dermatology and Venereology
Journal of the European Academy of Dermatology and Venereology
Volume 27, Issue 11, pages 1426–1432, November 2013
How to Cite
Méni, C., Bodemer, C., Toulon, A., Merhand, S., Perez-Cullell, N., Branchoux, S. and Taieb, C. (2013), Atopic dermatitis burden scale: creation of a specific burden questionnaire for families. Journal of the European Academy of Dermatology and Venereology, 27: 1426–1432. doi: 10.1111/jdv.12180
CT and SB are employed by Pierre Fabre Laboratories. SM is a consultant for the Foundation for Atopic Dermatitis, Pierre Fabre Laboratory. NPC is employed by Eau Thermale Avène. CM, CB and AT declare no conflict of interest.
This work was supported by the Public Health department of Pierre Fabre Laboratories.
- Issue published online: 16 OCT 2013
- Article first published online: 16 MAY 2013
- Manuscript Accepted: 10 APR 2013
- Manuscript Received: 20 NOV 2012
The notion of individual burden, associated with a disease, has been introduced to determine the ‘disability’ in the broadest sense (psychological, social, economic and physical). Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases with an estimated prevalence of 5%–30% in children.
To develop and validate a specific questionnaire which assess the burden of families of children with AD: the Atopic dermatitis Burden Scale (ABS).
Items for inclusion in ABS were initially generated from a literature review and a verbatim report from parents whose child had AD. ABS was refined via item reduction according to interquestion correlations, consensus among experts and exploratory factor analysis. Internal consistency was determined by calculating the Cronbach's α, concurrent validity by calculating the correlation between ABS and the Short-Form 12 items. Discriminant validity was analysed according to the severity degrees of AD assessed by Patient-Oriented SCORing index of Atopic Dermatitis (PO-SCORAD).
From an initial list of 29 items, ABS was reduced to a 14-item questionnaire, grouped into four dimensions based on the exploratory factor analysis. Construct validity was demonstrated and ABS showed good internal coherence (Cronbach's α: 0.78). ABS was significantly correlated to the mental dimension of Short-Form 12 (r = −0.49), but it was not correlated to the physical dimension (r = 0.04). ABS scores were significantly different according to the severity degrees of AD, with higher ABS score in parents whose child had severe AD.
The ABS questionnaire is a validated tool for assessing the burden of families of children with AD. An implementation of a prospective study is planned to estimate sensitivity to change and to confirm its domain structure in larger samples.