Get access

Cutaneous manifestations of the subtypes of polycystic ovary syndrome in Korean patients

Authors

  • J.S. Hong,

    1. Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea
    2. Acne and Rosacea Research Laboratory, Seoul National University Hospital, Seoul, Korea
    Search for more papers by this author
    • These authors equally contributed to this work as the first authors.
  • H.H. Kwon,

    1. Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea
    2. Acne and Rosacea Research Laboratory, Seoul National University Hospital, Seoul, Korea
    Search for more papers by this author
    • These authors equally contributed to this work as the first authors.
  • S.Y. Park,

    1. Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea
    2. Acne and Rosacea Research Laboratory, Seoul National University Hospital, Seoul, Korea
    Search for more papers by this author
  • J.Y. Jung,

    1. Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea
    2. Acne and Rosacea Research Laboratory, Seoul National University Hospital, Seoul, Korea
    Search for more papers by this author
  • J.Y. Yoon,

    1. Acne and Rosacea Research Laboratory, Seoul National University Hospital, Seoul, Korea
    Search for more papers by this author
  • S. Min,

    1. Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea
    2. Acne and Rosacea Research Laboratory, Seoul National University Hospital, Seoul, Korea
    Search for more papers by this author
  • Y.M. Choi,

    1. Department of Obstetrics and Gynecology, The Institute of Reproductive Medicine and Population, Medical Research Center, Seoul National University College of Medicine, Seoul, Korea
    Search for more papers by this author
  • D.H. Suh

    Corresponding author
    1. Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea
    2. Acne and Rosacea Research Laboratory, Seoul National University Hospital, Seoul, Korea
    Search for more papers by this author

  • Conflicts of interest

      Conflicts of interest
    • None declared.
  • Funding sources

      Funding sources
    • This work was supported by a grant number 03-2007-0290 from Seoul National University Hospital Research Fund and the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by Ministry of Education, Science and Technology (NFR-2010-0009075).

Abstract

Background

Polycystic ovary syndrome (PCOS) is a common endocrinological disorder in women of childbearing-age. Although PCOS has common dermatological manifestations, including hirsutism, acne and androgenetic alopecia, little is known about the dermatological characteristics of PCOS patients in Asia.

Objective

The goal of this study is to elucidate the dermatological characteristics and metabolic and hormonal parameters of Korean PCOS patients classified by the three ASRM/ESHERE criteria.

Methods

We investigated 40 untreated PCOS patients who were newly diagnosed in the Department of Obstetrics & Gynecology of Seoul National University Hospital. Patients were classified according to the presence of irregular menstruation (IM), polycystic ovary morphology (PCOM) and hyperandrogenism (HA). Acne specific questionnaire, physical examination, and blood sampling were thoroughly conducted.

Results

Twenty four patients (60.0%) met the criteria for the IM/HA/PCOM group and sixteen (40.0%) belonged to the IM/PCOM group. Acne was the most commonly observed dermatological manifestation (95.0%) followed by hirsutism (60.0%), seoborrhea (47.5%), acanthosis nigricans (20.0%) and androgenetic alopecia (12.5%). Hirsutism was more frequently observed in the IM/HA/PCOM group; the prevalence of other cutaneous manifestations did not differ significantly. Acne was most often observed on the face and most acne lesions were distributed on the forehead and cheek. Serum dehydroepiandrosterone sulphate level was higher in IM/HA/PCOM group, while serum cholesterol and high density lipoprotein concentrations were higher in the IM/PCOM group.

Conclusion

We described several dermatological manifestations and serum hormonal and metabolic parameters in Korean PCOS patients. Cutaneous manifestations might be the first signs of PCOS; therefore, dermatologists should be more aware of cutaneous manifestations of various ethnicities.

Get access to the full text of this article

Ancillary