Correlative light and electron microscopy for the analysis of cell division

Authors

  • STEFANIE REDEMANN,

    1. Structural Cell Biology Group, Experimental Center, Medical Faculty Carl Gustav Carus, University of Technology Dresden, Dresden, Germany
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  • THOMAS MÜLLER-REICHERT

    Corresponding author
    • Structural Cell Biology Group, Experimental Center, Medical Faculty Carl Gustav Carus, University of Technology Dresden, Dresden, Germany
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Correspondence to: Thomas Müller-Reichert, Structural Cell Biology Group, Experimental Center, Medical Faculty Carl Gustav Carus, University of Technology Dresden, Dresden 01307, Germany. Tel: (+49) 351 458-6442; Fax: (+49) 351 458-6305; e-mail: mueller-reichert@tu-dresden.de

Summary

Correlative light and electron microscopy (CLEM) has recently gained increasing attention, because it enables the acquisition of dynamic as well as ultrastructural information about subcellular processes. It is the power of combining the two imaging modalities that gives additional information as compared to using the imaging techniques separately. Here, we briefly summarize two CLEM approaches for the analysis of cells in mitosis and cytokinesis.

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