Post-injection sciatic neuropathy in a cynomolgus macaque (Macaca fascicularis)

Authors

  • C.A. Carrier,

    Corresponding author
    1. Veterinary Services, Nonclinical Safety Assessment at Covance Laboratories, Inc., Chandler, Arizona, USA
    • Correspondence

      Catherine A. Carrier, DVM, DACLAM,

      Veterinary Services, Nonclinical Safety Assessment at Covance Laboratories, Inc.,

      PO Box 20836 Mesa, Arizona, 85277, USA.

      Tel.: +1 206 685 1842;

      fax: +1 206 616 1710;

      e-mail: drcarrierdvm@gmail.com

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  • K.B. Donnelly

    1. Molecule Development Services, Nonclinical Safety Assessment at Covance Laboratories, Inc., Chandler, Arizona, USA
    Search for more papers by this author

Abstract

Background

Intramuscular injection is a common route parenteral used in primates.

Methods

A cynomolgus macaque was evaluated for acute lameness and atrophy of the left leg with no evidence of trauma.

Results

History revealed ketamine injection 12 days prior.

Conclusions

Histologic examination supported traumatic injection neuropathy due to intramuscular injection.

Ancillary